Deciphering the Chemical Structure and Properties of NADP
At NINGBO INNO PHAMMCHEM CO.,LTD., we believe a deep understanding of a molecule's chemical nature is key to unlocking its full potential. Beta-Nicotinamide Adenine Dinucleotide Phosphate (NADP) is a complex biomolecule with a fascinating structure that dictates its vital biological functions. Examining its beta-nicotinamide adenine dinucleotide phosphate chemical structure provides insight into its role as a coenzyme.
Structurally, NADP is a dinucleotide, meaning it is composed of two nucleotide units linked together. One of these nucleotides contains adenine, a fundamental base in DNA and RNA, attached to a ribose sugar and a phosphate group. The other nucleotide unit contains nicotinamide, a derivative of Vitamin B3, also attached to a ribose sugar and a phosphate group. The defining feature of NADP, distinguishing it from its close relative NAD (Nicotinamide Adenine Dinucleotide), is an additional phosphate group esterified to the 2'-hydroxyl group of the ribose sugar attached to the adenine moiety. This seemingly small addition significantly alters its cofactor specificity and thus its biochemical roles.
The overall molecular formula for NADP is C21H28N7O17P3, and its molecular weight is approximately 743.41 g/mol. These physicochemical properties are critical for analytical chemists and biochemists to verify product purity and concentration. The presence of multiple phosphate groups contributes to NADP's solubility in water, a necessary trait for its function in aqueous cellular environments. Information regarding beta-nicotinamide adenine dinucleotide phosphate chemical structure is crucial for researchers performing assays or developing new products.
The functional significance of NADP's structure is directly linked to its ability to act as an electron carrier. The nicotinamide ring is the site where oxidation and reduction reactions occur, accepting or donating a hydride ion (a proton and two electrons). This redox activity is central to its role in cellular respiration and biosynthesis. The additional phosphate group on the 2' position influences how NADP binds to specific enzymes, differentiating it from NAD and ensuring it participates in distinct metabolic pathways, particularly those related to anabolic processes and the generation of reducing power (NADPH).
For those seeking to buy NADP for research, understanding these structural and chemical properties is paramount. The purity of the compound, often determined by methods like HPLC, directly impacts the reliability of experimental results. NINGBO INNO PHARMCHEM CO.,LTD. ensures that our beta-nicotinamide adenine dinucleotide phosphate meets high purity standards, allowing researchers to confidently explore its applications.
In summary, the intricate chemical architecture of NADP, with its distinctive 2'-phosphate group, underpins its specialized functions as a coenzyme in crucial metabolic processes. A thorough understanding of its structure and properties is vital for its effective utilization in biochemical research and pharmaceutical development.
Perspectives & Insights
Bio Analyst 88
“This seemingly small addition significantly alters its cofactor specificity and thus its biochemical roles.”
Nano Seeker Pro
“The overall molecular formula for NADP is C21H28N7O17P3, and its molecular weight is approximately 743.”
Data Reader 7
“These physicochemical properties are critical for analytical chemists and biochemists to verify product purity and concentration.”