Demystifying Ferrocene Chemistry: A Look at (R)-(+)-N,N-Dimethyl-1-ferrocenylethylamine
Ferrocene chemistry, a fascinating branch of organometallic chemistry, offers a unique perspective on molecular design and reactivity. At NINGBO INNO PHARMCHEM CO.,LTD, we are dedicated to making these advanced chemical concepts accessible and providing the essential building blocks for research. Today, we turn our attention to a specific ferrocene derivative, (R)-(+)-N,N-Dimethyl-1-ferrocenylethylamine (CAS 31886-58-5), to illustrate the principles and applications of this versatile class of compounds.
At its heart, ferrocene is an organoiron compound with a distinctive structure: an iron atom sandwiched between two parallel cyclopentadienyl anions (Cp). This 'sandwich' structure imparts remarkable stability, particularly thermal stability, and unique electronic properties. These properties are inherited and often amplified in ferrocene derivatives, where one or more hydrogen atoms on the cyclopentadienyl rings are replaced by functional groups.
(R)-(+)-N,N-Dimethyl-1-ferrocenylethylamine exemplifies this functionalization. It incorporates an ethylamine moiety attached to one of the cyclopentadienyl rings, and crucially, it possesses a chiral center at the carbon atom bearing the amine group. This chirality, denoted by the (R) configuration, is what makes it particularly valuable in asymmetric synthesis. The molecule's physical characteristics include a brown liquid appearance, a molecular formula of C14H19FeN, and a molecular weight of 257.152.
The chemical utility of (R)-(+)-N,N-Dimethyl-1-ferrocenylethylamine is multifaceted. As a chiral amine, it can serve as a ligand in transition metal catalysis, influencing the stereochemical outcome of reactions. It is also a vital intermediate in the synthesis of pharmaceuticals and other fine chemicals where specific stereoisomers are required. Its role in creating chiral N-phosphoryl y-aminoboronates, for instance, showcases its importance in constructing complex, biologically active molecules. NINGBO INNO PHARMCHEM CO.,LTD is proud to supply this and other ferrocene derivatives, enabling researchers to delve deeper into the rich chemistry of these organometallic wonders and apply them to solve real-world challenges.
Perspectives & Insights
Quantum Pioneer 24
“The molecule's physical characteristics include a brown liquid appearance, a molecular formula of C14H19FeN, and a molecular weight of 257.”
Bio Explorer X
“The chemical utility of (R)-(+)-N,N-Dimethyl-1-ferrocenylethylamine is multifaceted.”
Nano Catalyst AI
“As a chiral amine, it can serve as a ligand in transition metal catalysis, influencing the stereochemical outcome of reactions.”