Eltrombopag Synthesis: The Role of 3-(2-methoxy-3-nitrophenyl)benzoic Acid
The development of targeted therapies for complex medical conditions often relies on specialized chemical compounds that act as building blocks. In the realm of hematology, Eltrombopag has emerged as a significant treatment for conditions involving low platelet counts. Central to its synthesis is the intermediate 3-(2-methoxy-3-nitrophenyl)benzoic acid, also known by its CAS number 376591-94-5. This article explores the importance of this compound in the chemical synthesis of Eltrombopag.
3-(2-methoxy-3-nitrophenyl)benzoic acid is characterized by its off-white to light brown powder appearance and a high assay of u226598.0%. These specifications are crucial for its role in the multi-step chemical synthesis of Eltrombopag, a TPO receptor agonist that aids in platelet production. The purity and consistency of this intermediate directly influence the efficiency of the manufacturing process and the ultimate quality of the Eltrombopag API.
Eltrombopag is a vital medication for patients diagnosed with chronic immune thrombocytopenia (ITP) and severe aplastic anemia (SAA), where it helps manage dangerously low platelet levels. The reliable production of Eltrombopag necessitates a secure and high-quality supply of its key intermediates. Pharmaceutical companies must therefore prioritize sourcing this Eltrombopag intermediate from reputable suppliers to ensure the continuity and integrity of their manufacturing operations. The ability to buy Eltrombopag intermediate with such stringent quality parameters is fundamental.
NINGBO INNO PHARMCHEM CO.,LTD. plays a pivotal role in this supply chain, providing essential pharmaceutical intermediates like 3-(2-methoxy-3-nitrophenyl)benzoic acid. Their commitment to stringent quality control and efficient production processes ensures that manufacturers have access to the reliable building blocks needed to produce critical medications, contributing to better patient outcomes in the treatment of blood disorders.
Perspectives & Insights
Nano Explorer 01
“plays a pivotal role in this supply chain, providing essential pharmaceutical intermediates like 3-(2-methoxy-3-nitrophenyl)benzoic acid.”
Data Catalyst One
“Their commitment to stringent quality control and efficient production processes ensures that manufacturers have access to the reliable building blocks needed to produce critical medications, contributing to better patient outcomes in the treatment of blood disorders.”
Chem Thinker Labs
“The development of targeted therapies for complex medical conditions often relies on specialized chemical compounds that act as building blocks.”