The Essential Properties and Synthesis of Diethyl D-Tartrate for Chemical Innovation
Diethyl D-Tartrate (CAS 13811-71-7) is a cornerstone molecule in organic synthesis, particularly valued for its well-defined chirality and versatility. As a derivative of tartaric acid, it inherits a specific stereochemical configuration that is crucial for its applications in the pharmaceutical and fine chemical industries. NINGBO INNO PHARMCHEM CO.,LTD. offers this high-quality compound, providing essential insights into its properties and synthesis to support chemical innovation.
The compound is typically characterized as a clear, colorless, and transparent viscous liquid. Its high purity, often exceeding 99%, and exceptionally high optical purity, also typically above 99%, are its most critical attributes. These specifications are essential for its role as a chiral building block, ensuring that downstream reactions proceed with the desired stereoselectivity. The chemical properties of Diethyl D-Tartrate, such as its solubility in common organic solvents like chloroform and its slight solubility in water, make it adaptable to various reaction conditions. Its relatively low melting point (around 17°C) and boiling point (162°C at 19 mmHg) are also important considerations for handling and processing.
The synthesis of Diethyl D-Tartrate typically involves the esterification of D-tartaric acid with ethanol. Various methods are employed to achieve high yields and purity, often involving acid catalysts such as hydrochloric acid or thionyl chloride. The refinement process is critical, commonly including steps like neutralization, filtration, and high-vacuum distillation to remove impurities and ensure the desired optical purity. NINGBO INNO PHARMCHEM CO.,LTD. adheres to rigorous protocols in its pharmaceutical intermediates manufacturing to guarantee the consistent quality of Diethyl D-Tartrate, which is vital for its use in the synthesis of chiral drugs.
The applications of Diethyl D-Tartrate extend beyond its role as a simple intermediate. It is a key component in many asymmetric catalysis applications, acting as a chiral ligand or auxiliary to control the stereochemical outcome of reactions. This ability to direct enantioselectivity is indispensable for creating single-enantiomer drugs, which are often more effective and have fewer side effects than their racemic counterparts. The compound also finds use as a food additive, further highlighting its diverse utility.
For researchers and manufacturers seeking reliable sources of chiral building blocks, understanding the properties and synthesis of Diethyl D-Tartrate is crucial. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing this essential material, supporting advancements in chiral synthesis, pharmaceutical development, and other sophisticated chemical processes. The availability of such high-quality intermediates fuels innovation and enables the creation of novel molecules with precise stereochemical control.
In summary, the physical and chemical properties of Diethyl D-Tartrate, coupled with its well-established synthesis routes, position it as a vital chiral intermediate. NINGBO INNO PHARMCHEM CO.,LTD. ensures that this compound meets the exacting standards required for cutting-edge research and industrial applications, particularly in the realm of chiral drug development and asymmetric catalysis.
Perspectives & Insights
Agile Reader One
“offers this high-quality compound, providing essential insights into its properties and synthesis to support chemical innovation.”
Logic Vision Labs
“The compound is typically characterized as a clear, colorless, and transparent viscous liquid.”
Molecule Origin 88
“Its high purity, often exceeding 99%, and exceptionally high optical purity, also typically above 99%, are its most critical attributes.”