The field of targeted protein degradation is rapidly advancing, with Proteolysis Targeting Chimeras (PROTACs) emerging as a powerful therapeutic strategy. These bifunctional molecules recruit specific proteins for cellular degradation, offering a new avenue for treating diseases that were previously considered undruggable. At the heart of successful PROTAC design lies the linker, a critical component that connects the target-binding warhead to the E3 ligase recruiter. NINGBO INNO PHARMCHEM CO.,LTD. is proud to supply 1,2-Bis(2-iodoethoxy)ethane (CAS: 36839-55-1), a versatile PEG-based linker essential for many PROTAC applications.

1,2-Bis(2-iodoethoxy)ethane is a well-established chemical intermediate, recognized for its utility in synthesizing various PROTAC molecules, including potent BTK degraders such as MT802 and SJF620. Its structure, featuring repeating ethylene oxide units, confers flexibility and favorable solubility characteristics, which are crucial for optimizing the binding affinity and cellular permeability of the final PROTAC conjugate. When considering the purchase of such specialized chemicals, understanding the supplier's commitment to quality and consistency is paramount. Sourcing from a reputable manufacturer in China, like NINGBO INNO PHARMCHEM CO.,LTD., can provide significant advantages in terms of both cost and reliability.

The chemical properties of 1,2-Bis(2-iodoethoxy)ethane make it an attractive choice for synthetic chemists. Its relatively high molecular weight (369.97 g/mol) and specific functional groups allow for precise chemical manipulations. The compound is typically supplied as a clear red-orange liquid, stable under ambient conditions, although it is advisable to store it below +30°C. For researchers involved in drug discovery, readily accessing this compound through a straightforward buy process ensures that their experimental timelines are met. The availability of this linker directly impacts the pace at which new PROTACs can be designed, synthesized, and tested.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting the pharmaceutical and biotechnology sectors by providing access to high-quality chemical intermediates. We understand that the price and availability of essential building blocks like 1,2-Bis(2-iodoethoxy)ethane can significantly influence research outcomes. By offering this vital linker, we aim to empower scientists in their pursuit of novel therapeutics, particularly in the realm of targeted protein degradation. Whether you are exploring new chemical synthesis pathways or scaling up production, our commitment is to be a trusted supplier, ensuring you receive the quality materials needed for success.