NINGBO INNO PHARMCHEM CO.,LTD. is a leading provider of specialized chemical intermediates, and a closer look at 4-(3-Chloropropyl)morpholine (CAS 7357-67-7) reveals its significant value in the pharmaceutical landscape. This compound, a derivative of morpholine, is indispensable for the synthesis of Gefitinib, a crucial tyrosine kinase inhibitor used in the treatment of certain types of cancer, most notably non-small cell lung cancer. Understanding its chemical profile is key to appreciating its utility.

The physical and chemical properties of 4-(3-Chloropropyl)morpholine are well-defined, contributing to its reliable performance in chemical synthesis. It is characterized as a colorless to light yellow clear liquid with a density of 1.062 g/cm³. Its melting point is -52°C, indicating it remains liquid even at very low temperatures, while its boiling point is 227.1°C, signifying stability under elevated thermal conditions. The flash point of 67°C also provides important safety information for handling and storage in industrial settings. These parameters are critical for ensuring consistent reaction outcomes.

A cornerstone of its utility in pharmaceutical manufacturing is its high purity, often specified at 98.0% or higher as measured by gas chromatography (GC). This level of purity, coupled with strict limits on single and total impurities (≤0.5% and ≤2.0%, respectively) and moisture content (≤0.5%), ensures that 4-(3-Chloropropyl)morpholine functions effectively as a building block without introducing detrimental side products. NINGBO INNO PHARMCHEM CO.,LTD. is committed to maintaining these high standards, making us a trusted partner for Gefitinib intermediate manufacturing.

The primary application of 4-(3-Chloropropyl)morpholine is its role as a key intermediate in the synthesis of Gefitinib. This complex organic molecule facilitates critical chemical transformations required to construct the active structure of the drug. Its presence ensures that the specific molecular architecture necessary for Gefitinib's targeted action against epidermal growth factor receptor (EGFR) tyrosine kinase is achieved. Beyond Gefitinib, the morpholine ring system within 4-(3-Chloropropyl)morpholine offers a versatile scaffold that can be adapted for the development of other novel pharmaceutical agents, positioning it as a valuable compound in broader drug development research.

For companies seeking to source this essential chemical, particularly from China, NINGBO INNO PHARMCHEM CO.,LTD. offers a strategic advantage. We provide access to high-quality materials that meet stringent specifications, backed by robust manufacturing capabilities. Our focus on quality control and customer service ensures that clients receive reliable products that support their research and production needs, solidifying our reputation as a premier pharmaceutical intermediate supplier.

In summary, the detailed chemical properties and critical applications of 4-(3-Chloropropyl)morpholine underscore its importance in modern medicine. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying this vital intermediate, contributing to advancements in cancer therapy and pharmaceutical innovation.