4-Iodoaniline, identified by its CAS number 540-37-4, is a compound of significant interest in chemical research due to its distinct chemical properties and broad applicability in organic synthesis and material science. As a derivative of aniline, it features an iodine atom attached to the benzene ring, a structural element that grants it unique reactivity and makes it a valuable tool for chemists exploring new synthetic pathways and functional materials.

The molecular formula of 4-iodoaniline is C6H6IN, and its structure is characterized by the para-substitution of an iodine atom on the aniline ring. This iodine atom is a key feature, as it serves as an excellent leaving group in various nucleophilic substitution reactions and is highly reactive in metal-catalyzed cross-coupling reactions, such as Suzuki, Sonogashira, and Heck couplings. These reactions are fundamental in modern organic synthesis, enabling the construction of complex carbon-carbon bonds and the formation of intricate molecular architectures. Researchers frequently employ 4-iodoaniline to introduce aryl iodide moieties into target molecules, facilitating subsequent functionalization.

In research settings, 4-iodoaniline finds extensive use as a building block. For example, it has been utilized in the preparation of phenyl functionalized graphene oxide (I-Ph-GO), a material with potential applications in advanced electronics and composite materials. The ability to incorporate iodine-substituted phenyl groups onto graphene oxide highlights the compound's role in developing novel functionalized nanomaterials. Furthermore, palladium-catalyzed carbonylation reactions involving 4-iodoaniline have led to the synthesis of polybenzamides, materials known for their thermal stability and mechanical strength, relevant in engineering plastics and high-performance fibers.

The study of reaction mechanisms and the development of new synthetic methodologies are also areas where 4-iodoaniline plays a role. Its predictable reactivity makes it a suitable substrate for testing new catalytic systems or reaction conditions. For instance, researchers have explored its conversion into specific distonic isomers of ionized aniline, aiding in the fundamental understanding of chemical ionization processes. This deep dive into its chemical behavior contributes to the broader advancement of chemical science.

For research institutions and laboratories, sourcing high-quality 4-iodoaniline is crucial for reliable experimental results. The availability of consistent, high-purity 4-iodoaniline from reputable suppliers, such as NINGBO INNO PHARMCHEM CO.,LTD., ensures the reproducibility of experiments and the successful execution of complex synthetic strategies. When engaging in research that requires 4-iodoaniline, understanding its precise specifications and handling guidelines is essential. The compound is typically supplied as a powder and requires appropriate storage conditions to maintain its integrity.

The continued exploration of 4-iodoaniline's chemical properties promises further contributions to material science and synthetic organic chemistry. As researchers seek to develop more efficient synthetic routes and innovative materials, the versatile reactivity of 4-iodoaniline will undoubtedly remain a valuable asset in their toolkit. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting the scientific community by providing access to this essential research chemical, fostering advancements in chemical discovery and application.

By offering 4-iodoaniline, NINGBO INNO PHARMCHEM CO.,LTD. supports the critical work of researchers worldwide, enabling them to push the boundaries of chemical innovation. The compound's utility in creating advanced materials and facilitating complex syntheses makes it indispensable for ongoing scientific exploration.