At NINGBO INNO PHARMCHEM CO.,LTD., we specialize in providing essential chemical building blocks that drive innovation in various industries, particularly pharmaceuticals. One such critical compound is (R)-5-(2-Aminopropyl)-1-(3-benzyloxypropyl)indoline-7-carbonitrile (CAS 459868-73-6). This indoline derivative is highly valued for its precise chemical structure and purity, making it an indispensable component in advanced organic synthesis and the manufacturing of Active Pharmaceutical Ingredients (APIs).

The compound's physicochemical characteristics are key to its utility. Presented as a white to off-white powder, its assay is guaranteed to be at least 98.0%, ensuring a high degree of purity critical for pharmaceutical applications. With a molecular formula of C22H27N3O and a molecular weight of 349.469 g/mol, it possesses a density of approximately 1.1 g/cm³, a boiling point of 539.3 °C at 760 mmHg, and a flash point of 280 °C. These properties highlight its stability and manageable handling characteristics in industrial settings. The presence of the indoline core, coupled with the aminopropyl and benzyloxypropyl side chains, provides specific reactive sites that are leveraged in complex synthetic pathways.

The primary application for (R)-5-(2-Aminopropyl)-1-(3-benzyloxypropyl)indoline-7-carbonitrile is as a key intermediate in the production of Silodosin. Silodosin is a selective alpha-1a adrenoceptor antagonist used to treat the symptoms of benign prostatic hyperplasia. The specific stereochemistry, indicated by the (R) configuration, is crucial for the drug's efficacy, ensuring the correct biological interaction. Beyond its role in Silodosin synthesis, this versatile compound serves as a valuable building block for other specialty chemical syntheses and in pharmaceutical research, where its unique indoline structure can be explored for novel therapeutic agents. For companies seeking to buy (R)-5-(2-aminopropyl)-1-(3-benzyloxypropyl)indoline-7-carbonitrile, NINGBO INNO PHARMCHEM CO.,LTD. offers a reliable source for this high-quality intermediate, supporting innovation and development in the chemical and pharmaceutical sectors.