The field of organic chemistry offers a vast array of molecules, each with unique properties and potential applications. Among these, certain compounds stand out for their critical roles in specific industries. Methyl 2-Methoxy-5-Sulfamoylbenzoate (CAS: 33045-52-2) is one such compound, primarily recognized for its utility as a pharmaceutical intermediate. This article, brought to you by NINGBO INNO PHARMCHEM CO.,LTD., aims to provide a comprehensive overview of its chemical composition, physical attributes, and the significant applications that make it a valuable asset in the pharmaceutical sector.

At its core, Methyl 2-Methoxy-5-Sulfamoylbenzoate is an organic compound with the molecular formula C9H11NO5S. This formula indicates a structure containing a benzene ring substituted with a methoxy group (-OCH3), a sulfamoyl group (-SO2NH2), and a methyl ester group (-COOCH3). The molecular weight is approximately 245.252 g/mol. These functional groups bestow upon the molecule specific reactivity and solubility characteristics, making it suitable for complex organic synthesis. Its physical appearance is typically a white or almost white crystalline powder, a testament to its purity when manufactured under controlled conditions.

Delving into its physical and chemical properties provides further insight into its utility. The melting point, generally reported to be between 175-177 °C, is a key indicator of its crystalline structure and purity. A well-defined melting point range suggests a high degree of molecular order and minimal impurities. The boiling point, noted at 439.8±55.0 °C at 760 mmHg, indicates its thermal stability at elevated temperatures, which is important for certain reaction conditions. The compound also exhibits a relatively high flash point, around 219.8±31.5 °C, contributing to its safe handling and storage. Specifications often detail a low loss on drying (≤0.5%), minimal other impurities (≤1.0%), and a controlled acid value (≤2.0%), all of which are critical parameters for its use in pharmaceutical manufacturing.

The predominant application for Methyl 2-Methoxy-5-Sulfamoylbenzoate is its role as a vital intermediate in the synthesis of Amisulpride, a widely prescribed antipsychotic medication. This compound provides the essential chemical scaffold upon which the Amisulpride molecule is constructed through a series of targeted chemical reactions. The specific arrangement of functional groups within Methyl 2-Methoxy-5-Sulfamoylbenzoate is precisely what is needed to efficiently form the Amisulpride structure. Given the increasing global demand for effective psychiatric treatments, the importance of reliable suppliers for this intermediate cannot be overstated. Manufacturers looking for a high purity methyl 2-methoxy-5-sulfamoylbenzoate or a trusted CAS 33045-52-2 pharmaceutical intermediate supplier can find valuable resources in the market, with China being a prominent source.

As NINGBO INNO PHARMCHEM CO.,LTD., we pride ourselves on providing high-quality chemical intermediates that meet the exacting standards of the pharmaceutical industry. Our expertise in fine chemical synthesis and our commitment to rigorous quality control ensure that our Methyl 2-Methoxy-5-Sulfamoylbenzoate is a reliable choice for your production needs. We understand the intricacies of drug synthesis and are dedicated to supporting our clients with consistent product quality and supply chain stability. Whether you are involved in large-scale production or specialized research, our company is poised to meet your requirements for this critical sulfonamide drug intermediate.