1,2,3-1H-Triazole, identified by CAS number 288-36-8, is a fascinating heterocyclic compound that holds significant importance in the field of chemistry, particularly in organic synthesis and pharmaceutical development. At NINGBO INNO PHARMCHEM CO.,LTD., we are deeply invested in understanding and providing high-quality intermediates like 1,2,3-1H-Triazole to our clients.

Chemically, 1,2,3-1H-Triazole (C2H3N3) is characterized by a five-membered ring containing two carbon atoms and three nitrogen atoms arranged consecutively. This aromatic heterocyclic structure lends it a surprising degree of stability. Its molecular weight is approximately 69.07 g/mol. A key physical attribute is its appearance as a colorless liquid, with a reported melting point between 23-25°C. This means it can exist as a solid or liquid depending on ambient temperatures, a characteristic that can influence handling and storage protocols. The high purity of 1,2,3-1H-Triazole, typically assaying ≥99.5%, and its low water content (≤0.5%) are crucial for its reliable performance in complex chemical reactions.

The synthesis of 1,2,3-triazoles, including the unsubstituted parent compound, has been extensively studied. While historically, methods involving hydrazoic acid and acetylene were used, modern synthesis often relies on more controlled and safer approaches. The 'click chemistry' methodology, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), has revolutionized the synthesis of 1,2,3-triazole derivatives, offering high yields and regioselectivity. Researchers are continuously exploring new catalytic systems and reaction conditions to improve efficiency and sustainability. For any chemical supplier, understanding these synthetic pathways is key to ensuring product quality and consistent availability. NINGBO INNO PHARMCHEM CO.,LTD. stays abreast of these developments to offer the best possible products.

The applications of 1,2,3-1H-Triazole are primarily rooted in its role as a pharmaceutical intermediate. It serves as a critical building block in the synthesis of molecules like tazobactam, an important component in combating antibiotic resistance. Its structural motif is also recognized as a bioisostere for other functional groups in medicinal chemistry, allowing for the fine-tuning of drug properties. The demand for such intermediates drives continuous innovation in chemical manufacturing. If you are looking for a reliable 1,2,3-1H-Triazole supplier, NINGBO INNO PHARMCHEM CO.,LTD. offers premium grade products.

In summary, 1,2,3-1H-Triazole is a compound of significant chemical interest and practical value. Its unique structure, properties, and synthetic accessibility make it an essential component in the pharmaceutical industry. NINGBO INNO PHARMCHEM CO.,LTD. is committed to advancing chemical synthesis by providing high-quality 1,2,3-1H-Triazole to support research and industrial applications. For inquiries about 1,2,3-1H-Triazole buy options or to learn more about our product range, please contact us.