NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to advancing chemical understanding, and this article focuses on the fundamental aspects of 4-Chloro-3-fluorobenzoic acid (CAS: 403-17-8). As a critical component in many industrial processes, understanding its synthesis and chemical properties is key to leveraging its full potential. This compound, a halogenated benzoic acid derivative, is prized for its precise molecular structure and high reactivity, making it an indispensable organic synthesis building block.

The 4-Chloro-3-fluorobenzoic acid synthesis typically involves meticulous halogenation reactions. Starting materials like fluorobenzoic acid derivatives are subjected to chlorination under controlled conditions, often employing catalysts and specific temperature ranges to ensure regioselectivity and minimize by-products. The optimization of these reaction conditions, including solvent choice and reaction time, is crucial for achieving the high purity levels, typically exceeding 99.0%, that are essential for its downstream applications. This focus on quality is a hallmark of NINGBO INNO PHARMCHEM CO.,LTD.'s production standards.

Chemically, 4-Chloro-3-fluorobenzoic acid exhibits characteristics that make it highly valuable. Its density is approximately 1.477 g/cm³, with a melting point in the range of 190-192°C and a boiling point of 287.4°C. These physical properties, along with its flash point of 127.6°C, provide important safety and handling information. The presence of both chlorine and fluorine atoms on the benzene ring influences its electronic properties, enabling it to participate in a wide array of chemical transformations, from nucleophilic substitutions to coupling reactions. These versatile uses of 4-Chloro-3-fluorobenzoic acid are fundamental to its role as an intermediate.

As a reliable 4-Chloro-3-fluorobenzoic acid supplier, NINGBO INNO PHARMCHEM CO.,LTD. ensures that researchers and manufacturers have access to this vital chemical. Understanding the precise purity of 4-Chloro-3-fluorobenzoic acid and the detailed synthesis routes allows our clients to confidently integrate it into their projects, whether in pharmaceutical development, agrochemical formulation, or material science. We are committed to providing high-quality chemical solutions that drive innovation.