NINGBO INNO PHARMCHEM CO.,LTD. is pleased to offer insights into the synthesis and chemical properties of Methyl 4,6-dichloronicotinate, a key compound known by its CAS number 65973-52-6. Understanding these aspects is vital for researchers and manufacturers who rely on this versatile intermediate for their chemical synthesis needs. This dichloro-substituted pyridine derivative presents a unique combination of reactivity and stability, making it a valuable asset in various chemical processes.

Physically, Methyl 4,6-dichloronicotinate typically appears as a white powder. Its melting point is generally reported in the range of 41-43°C, and it possesses a density of approximately 1.426 g/cm³. For optimal preservation of its chemical integrity, storage under an inert atmosphere, such as nitrogen or argon, at temperatures between 2-8°C is recommended. These conditions help maintain the purity and reactivity of the compound, ensuring its suitability for demanding synthetic applications. The ability to buy Methyl 4,6-dichloronicotinate from reliable sources like NINGBO INNO PHARMCHEM CO.,LTD. guarantees that these storage and handling protocols have been meticulously followed.

The synthesis of Methyl 4,6-dichloronicotinate often starts from methyl 4,6-dihydroxynicotinate. A common synthetic route involves reaction with phosphoryl chloride in the presence of N,N-diethylaniline at elevated temperatures. The subsequent purification steps, which may include chromatography, yield the desired product with high purity. The effectiveness of this chemical synthesis process is crucial for its widespread use as a pharmaceutical intermediate and agrochemical intermediate. The detailed understanding of these CAS 65973-52-6 uses and synthesis methods allows NINGBO INNO PHARMCHEM CO.,LTD. to provide a superior product.

As a key building block, Methyl 4,6-dichloronicotinate is often involved in hydrolysis reactions, such as its conversion to 4,6-dichloronicotinic acid. This reactivity underscores its importance in multi-step synthesis strategies. The meticulous attention to detail in the production and handling of this pyridine derivative ensures that it meets the stringent requirements of the pharmaceutical and agrochemical industries. NINGBO INNO PHARMCHEM CO.,LTD. remains at the forefront, supplying this essential chemical with unwavering commitment to quality and customer satisfaction.