The successful formulation of pharmaceuticals relies heavily on the selection of appropriate excipients that facilitate efficient manufacturing processes and ensure the desired therapeutic effect. Copovidone VA64, a copolymer of N-vinylpyrrolidone and vinyl acetate, has emerged as a key ingredient in modern pharmaceutical manufacturing due to its unique properties as both a binder and a film-former. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of this vital compound, offering pharmaceutical-grade materials that meet the industry’s demanding standards.

Copovidone VA64, often denoted by its CAS number 25086-89-9, is a white to slightly yellowish, free-flowing powder. Its composition, typically a 60:40 ratio of NVP to VA, imbues it with a lower glass transition temperature and reduced hygroscopicity compared to traditional povidone (PVP). These characteristics are crucial for its performance in various pharmaceutical operations. The excellent copovidone solubility properties allow for its use in a range of solvents, facilitating its incorporation into diverse formulations.

In tablet manufacturing, Copovidone VA64 serves as an exceptionally effective binder. It is employed in wet granulation, dry granulation, and direct compression methods to enhance the mechanical strength and compressibility of granules and powders. This results in tablets that are more robust, less prone to chipping or breaking, and possess consistent hardness. Manufacturers appreciate the reliable performance of a high-quality copovidone VA64 tablet binder when aiming for efficient production and reproducible tablet quality.

Beyond its binding capabilities, Copovidone VA64 is widely utilized as a film-forming agent for tablet coatings. The films it produces are permeable, flexible, and adhere well to the tablet core. These coatings serve multiple purposes, including masking the taste of bitter APIs, protecting sensitive drugs from moisture and light, and improving the overall aesthetic appeal of the final product. As a leading provider of PVP VA64 pharmaceutical grade excipients, NINGBO INNO PHARMCHEM CO.,LTD. ensures that these film-forming agents contribute to the stability and efficacy of the final dosage form.

The versatility of Copovidone VA64 also extends to more specialized applications, such as its use in solid dispersions to improve the bioavailability of poorly soluble drugs and in controlled-release systems. Its unique polymer characteristics allow formulators to design advanced drug delivery strategies that enhance therapeutic outcomes. NINGBO INNO PHARMCHEM CO.,LTD. remains committed to supporting pharmaceutical innovation by supplying high-purity Copovidone VA64, enabling the development of next-generation medicines.