Exploring the Chemical Properties and Applications of 1-Acetyl-2-imidazolidinone (CAS 5391-39-9)
Understanding the fundamental properties of chemical compounds is essential for their effective utilization in research and industry. 1-Acetyl-2-imidazolidinone (CAS 5391-39-9) is a fine chemical that possesses a distinct set of characteristics, making it a valuable asset in various chemical applications, particularly in the pharmaceutical sector. NINGBO INNO PHARMCHEM CO.,LTD. emphasizes the importance of these properties for researchers seeking reliable synthetic materials.
Physically, 1-Acetyl-2-imidazolidinone presents as a white to off-white solid. Its melting point, typically observed in the range of 173-175°C, is a key indicator of its purity and stability. This well-defined melting point is crucial for processes that require precise temperature control during reactions or formulation. Solubility data indicates that it is sparingly soluble in chloroform and DMSO, and slightly soluble in methanol, even when heated. This solubility profile guides its use in different reaction media and purification methods.
Chemically, 1-Acetyl-2-imidazolidinone is recognized for its utility as a synthetic reagent. Its molecular formula, C5H8N2O2, and molecular weight of 128.13 g/mol provide the basic building blocks for its reactivity. As mentioned, its primary application is as an intermediate in the synthesis of pharmaceuticals, notably moxonidine. This involves incorporating the acetylated imidazolidinone structure into larger molecules, facilitating the creation of complex drug candidates. Furthermore, its role as an impurity standard, such as Clonidine Impurity A, is critical for analytical chemists and quality assurance departments. By having a pure sample of 1-Acetyl-2-imidazolidinone, laboratories can develop and validate methods to detect and quantify this impurity in pharmaceutical products, ensuring compliance with stringent regulatory standards.
The production of 1-Acetyl-2-imidazolidinone often involves the acetylation of 2-imidazolidinone. This reaction highlights the compound's lineage and its relationship to other important heterocyclic compounds. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying this compound with consistent quality, supporting its diverse applications from basic chemical research to advanced pharmaceutical manufacturing. By understanding and leveraging the chemical properties of 1-Acetyl-2-imidazolidinone, scientists can unlock its full potential in developing new and improved chemical processes and products.
Perspectives & Insights
Logic Thinker AI
“emphasizes the importance of these properties for researchers seeking reliable synthetic materials.”
Molecule Spark 2025
“Its melting point, typically observed in the range of 173-175°C, is a key indicator of its purity and stability.”
Alpha Pioneer 01
“This well-defined melting point is crucial for processes that require precise temperature control during reactions or formulation.”