Exploring the Chemical Properties and Applications of (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine
In the realm of advanced chemical synthesis and pharmaceutical research, understanding the detailed properties of key compounds is fundamental. NINGBO INNO PHARMCHEM CO.,LTD. presents a comprehensive look at (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine (CAS: 863329-66-2), a molecule whose specific attributes make it indispensable for critical applications, particularly in antiviral drug development. This compound, often referred to by synonyms such as PSI-6206 or RO 2433, plays a significant part in the intricate processes of creating modern pharmaceuticals.
The chemical identity of (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine is defined by its molecular formula, C10H13FN2O5, and a precise molecular weight of 260.21900. These parameters are crucial for stoichiometric calculations and ensuring the correct molecular interactions in synthetic reactions. Physically, it is typically presented as a fine white to off-white powder. Its melting point, recorded at 237-238°C, indicates a stable crystalline structure, which is advantageous for handling and storage in laboratory and industrial settings. The purity specifications, commonly exceeding 98.0%, guarantee that the compound is free from significant impurities that could interfere with downstream reactions or compromise the quality of the final product.
The utility of (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine extends across several vital areas of pharmaceutical R&D. As a Sofosbuvir synthesis intermediate, it is a direct precursor in the manufacturing of a leading antiviral medication for Hepatitis C. This application highlights its role in the supply chain for essential medicines. Furthermore, its classification as a nucleoside analog for antiviral research allows scientists to investigate its potential biological activities and to design related compounds with improved efficacy or altered pharmacokinetic profiles. The compound's status as a HCV replication inhibitor metabolite makes it a valuable tool for studying viral biology and identifying new therapeutic targets.
The detailed specifications and consistent quality of this chemical are crucial for reliable research outcomes. For instance, its low water content (≤0.5%) and loss on drying (≤1.0%) reflect its stability and low susceptibility to degradation. These properties are critical for companies involved in pharmaceutical intermediate manufacturing. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to meeting these high standards, providing researchers and manufacturers with a dependable source of this vital compound. By ensuring the quality and availability of (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine chemical properties, we support the advancement of drug discovery and the development of effective treatments for challenging diseases.
Perspectives & Insights
Molecule Vision 7
“The utility of (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine extends across several vital areas of pharmaceutical R&D.”
Alpha Origin 24
“As a Sofosbuvir synthesis intermediate, it is a direct precursor in the manufacturing of a leading antiviral medication for Hepatitis C.”
Future Analyst X
“Furthermore, its classification as a nucleoside analog for antiviral research allows scientists to investigate its potential biological activities and to design related compounds with improved efficacy or altered pharmacokinetic profiles.”