Methyl Bromopyruvate, a compound with the CAS number 7425-63-0, is a significant player in the chemical industry, primarily recognized for its role as an intermediate in the synthesis of Thiabendazole. This light yellow liquid is valued for its specific chemical properties and its contribution to the production of essential agrochemicals.

The compound, also known as methyl 3-bromo-2-oxopropanoate, exhibits a range of physical and chemical properties that are crucial for its effective utilization. With a density of approximately 1.7 g/cm³ and a boiling point around 186.8 °C at standard atmospheric pressure, it possesses characteristics typical of many organic intermediates. Its flash point of approximately 66.8 °C indicates moderate flammability, necessitating appropriate safety precautions during handling and storage. Understanding these methyl bromopyruvate properties is fundamental for process design and safety management in chemical manufacturing.

The high purity, typically ≥98.0% as confirmed by methyl bromopyruvate assay, ensures that the compound performs consistently in complex chemical reactions. This is particularly important when it functions as a methyl bromopyruvate intermediate in multi-step synthesis. The reliability of the intermediate directly translates to the quality and yield of the final product, be it an agrochemical or a compound intended for other industrial uses.

The primary among methyl bromopyruvate applications is its role in the synthesis of Thiabendazole, a broad-spectrum benzimidazole fungicide and parasiticide. The chemical structure of Methyl Bromopyruvate makes it an ideal precursor, allowing for efficient ring formation and functionalization in the Thiabendazole synthesis pathway. This critical application highlights its importance in agricultural science and the protection of crops from fungal diseases.

Furthermore, the reactive nature of Methyl Bromopyruvate opens doors to its use in other areas of organic synthesis. As a brominated α-keto ester, it can participate in a variety of reactions, including nucleophilic substitutions, cyclizations, and additions. This versatility makes it a valuable compound for researchers developing new synthetic methodologies or creating novel chemical entities with specific functionalities. The exploration of methyl bromopyruvate synthesis routes also contributes to the broader knowledge base of chemical manufacturing.

The packaging of Methyl Bromopyruvate is typically in 200 kg drums, designed to ensure product integrity during transport and storage. Proper storage in a cool, ventilated place is recommended to maintain its quality and reactivity over time. As with any chemical substance, adhering to safety guidelines and understanding its potential hazards is paramount. Consulting Material Safety Data Sheets (MSDS) and following recommended handling procedures are essential steps for any user.

In summary, Methyl Bromopyruvate is a high-purity chemical intermediate with well-defined properties that make it indispensable for key industrial applications, particularly in the agrochemical sector. Its role in Thiabendazole synthesis and its potential in broader organic chemistry underscore its significance in the chemical manufacturing landscape.