At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to supplying high-quality chemical products that serve as foundational elements for innovation across various industries. Methyl 2-iodobenzoate (CAS: 610-97-9) stands out as a particularly versatile organic intermediate, prized for its unique reactivity and broad utility in sophisticated organic synthesis. While its application in pharmaceutical intermediate production, especially for Montelukast, is well-established, its role extends significantly into fine chemical manufacturing and advanced research endeavors. This article explores the multifaceted applications and chemical characteristics that make Methyl 2-iodobenzoate an indispensable compound for chemists worldwide.

Methyl 2-iodobenzoate, chemically known as Methyl o-iodobenzoate or 2-Iodobenzoic acid methyl ester, boasts a molecular formula of C8H7IO2 and a molecular weight of 262.04400. Its physical properties are noteworthy: typically appearing as a light yellow to orange liquid, it has a density around 1.784 g/mL at 25°C and a boiling point of approximately 149-150°C at 10 mm Hg. These characteristics, coupled with a purity of 98% or more, ensure its suitability for precise chemical reactions where consistency is key. The compound's structure, featuring an aromatic ring with an iodine substituent and a methyl ester group in ortho positions, provides multiple reactive sites for synthetic chemists to exploit.

The versatility of Methyl 2-iodobenzoate in organic synthesis is a direct consequence of its reactive functional groups. The carbon-iodine bond is susceptible to various transformations, including palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck couplings), which are fundamental for forming new carbon-carbon bonds. These reactions are critical for assembling complex organic structures, a common requirement in the synthesis of fine chemicals, agrochemicals, and advanced materials. Furthermore, the iodine atom can be readily replaced by other nucleophiles or undergo radical reactions, offering diverse synthetic pathways. The methyl ester group can also be modified through hydrolysis to the corresponding carboxylic acid, transesterification, or reduction to an alcohol, further expanding its synthetic potential.

In the realm of fine chemical production, Methyl 2-iodobenzoate serves as a key intermediate for a wide array of specialized molecules. Its use in constructing heterocyclic compounds, which are prevalent in many biologically active molecules and functional materials, is particularly significant. Researchers are continually exploring new applications for this compound, including its potential in the development of novel catalysts, advanced polymers, and electronic materials. For instance, its derivatives might be incorporated into organic light-emitting diodes (OLEDs) or other optoelectronic devices due to the presence of aromatic systems and potential for extended conjugation.

Sourcing high-quality Methyl 2-iodobenzoate is essential for any chemical synthesis project. NINGBO INNO PHARMCHEM CO.,LTD. is a leading provider of this intermediate, ensuring exceptional purity and reliable supply for both research and industrial needs. We offer comprehensive product specifications and technical support to assist our clients in their synthetic endeavors. Whether you are engaged in pharmaceutical research, fine chemical manufacturing, or developing new advanced materials, partnering with a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. for your Methyl 2-iodobenzoate requirements will ensure the success and efficiency of your projects. We invite you to contact us to learn more about our product offerings and how we can support your chemical synthesis needs.