Fmoc-Lys-OH HCl: A Versatile Amino Acid Derivative for Bioconjugation and Beyond
At NINGBO INNO PHARMCHEM CO.,LTD., we understand the intricate needs of modern scientific research. Today, we shine a spotlight on Fmoc-Lys-OH HCl (CAS 139262-23-0), a versatile protected amino acid derivative that plays a critical role in advancing various scientific disciplines, from peptide synthesis to cutting-edge bioconjugation techniques.
Fmoc-Lys-OH HCl is a protected form of the amino acid lysine, widely employed in solid-phase peptide synthesis (SPPS). The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a temporary protecting group for the alpha-amino moiety of lysine. This protection strategy is fundamental to SPPS, allowing for controlled, step-by-step elongation of peptide chains. The key advantage of Fmoc chemistry lies in its mild deprotection conditions, typically involving a base like piperidine. This approach is compatible with a wide range of side chain protecting groups and is less harsh than acid-based deprotection methods, making it ideal for synthesizing complex or modified peptides. The availability of high-quality Fmoc-Lys-OH HCl is crucial for researchers aiming for efficiency and high yields.
The lysine side chain in Fmoc-Lys-OH HCl possesses a terminal primary amino group, which, once deprotected, can be readily functionalized. This inherent reactivity makes it an exceptionally valuable building block for various applications beyond simple peptide chain elongation. In bioconjugation, this free amino group can be used to covalently link the synthesized peptide to other biomolecules. For instance, it can be attached to antibodies to create targeted antibody-drug conjugates (ADCs), enabling precise delivery of cytotoxic agents to specific cells. It can also be used to link peptides to carrier proteins for vaccine development, or to nanoparticles for advanced drug delivery systems. The ability to purchase Fmoc-Lys-OH HCl from a reliable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures the quality and consistency needed for these sophisticated applications.
Furthermore, Fmoc-Lys-OH HCl is a critical component in the development of novel peptide-based therapeutics. Lysine's side chain can be modified to impart specific properties, such as increased solubility, enhanced receptor binding, or improved metabolic stability. This makes it invaluable in the pharmaceutical industry for designing peptides with optimized therapeutic profiles. Its application in protein engineering also allows scientists to introduce specific modifications or labels onto proteins, aiding in the study of protein function and interaction networks.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting scientific innovation by providing top-tier Fmoc-Lys-OH HCl. Our rigorous quality control ensures the purity and integrity of our products, making them ideal for demanding applications in bioconjugation, drug discovery, and advanced peptide synthesis. Trust NINGBO INNO PHARMCHEM CO.,LTD. to deliver the essential reagents that drive scientific breakthroughs.
Perspectives & Insights
Nano Explorer 01
“This makes it invaluable in the pharmaceutical industry for designing peptides with optimized therapeutic profiles.”
Data Catalyst One
“Its application in protein engineering also allows scientists to introduce specific modifications or labels onto proteins, aiding in the study of protein function and interaction networks.”
Chem Thinker Labs
“is committed to supporting scientific innovation by providing top-tier Fmoc-Lys-OH HCl.”