Fmoc-(R)-3-Amino-4-(3,4-difluorophenyl)butyric Acid: A Versatile Intermediate for Niche Pharmaceutical Applications
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing specialized chemical intermediates that cater to the evolving needs of the pharmaceutical industry. Fmoc-(R)-3-Amino-4-(3,4-difluorophenyl)butyric acid (CAS: 269396-60-3) is a prime example of such a versatile compound, finding utility in various niche pharmaceutical applications. Its unique structural features make it an attractive starting material for synthesizing complex molecules with targeted therapeutic effects.
The compound's structure combines several elements that are highly valued in drug design. The Fmoc protecting group is a standard for controlled peptide chain elongation, making it a key peptide synthesis chemical. This is crucial for researchers developing peptide-based drugs, which are gaining traction for their specificity and biocompatibility. Beyond traditional peptide synthesis, this molecule serves as an advanced pharmaceutical building block for creating non-peptide small molecules as well.
The 3,4-difluorophenyl group is particularly significant. Fluorine atoms can dramatically alter a molecule's lipophilicity, pKa, and conformational preferences, leading to improved membrane permeability, increased metabolic stability, and enhanced binding to target proteins. This makes the difluorophenyl butyric acid derivative an excellent choice for designing drug candidates with optimized pharmacokinetic and pharmacodynamic profiles. NINGBO INNO PHARMCHEM CO.,LTD. supplies this intermediate to facilitate such precise molecular engineering.
Furthermore, the inherent chirality of the molecule, specified as the (R)-enantiomer, is essential for applications where stereoselectivity is critical. This is often the case in the development of active pharmaceutical ingredients (APIs) where only one enantiomer exhibits the desired therapeutic effect, while the other may be inactive or even harmful. By providing this enantiomerically pure compound, NINGBO INNO PHARMCHEM CO.,LTD. supports the development of safer and more effective drugs. This is why it's highly valued in custom synthesis services for specialized research projects.
The versatility of Fmoc-(R)-3-Amino-4-(3,4-difluorophenyl)butyric acid extends to its use as a medicinal chemistry intermediate. It can be readily modified and incorporated into diverse molecular scaffolds, opening pathways to a wide array of novel therapeutic agents. Whether the goal is to develop new antibiotics, antivirals, oncology drugs, or agents for central nervous system disorders, this compound provides a reliable and adaptable starting point.
In conclusion, Fmoc-(R)-3-Amino-4-(3,4-difluorophenyl)butyric acid from NINGBO INNO PHARMCHEM CO.,LTD. is a potent intermediate with broad applicability in niche pharmaceutical research. Its combination of a protective group, a fluorinated moiety, and defined chirality makes it an indispensable tool for scientists pushing the boundaries of drug discovery and development.
Perspectives & Insights
Bio Analyst 88
“It can be readily modified and incorporated into diverse molecular scaffolds, opening pathways to a wide array of novel therapeutic agents.”
Nano Seeker Pro
“Whether the goal is to develop new antibiotics, antivirals, oncology drugs, or agents for central nervous system disorders, this compound provides a reliable and adaptable starting point.”
Data Reader 7
“In conclusion, Fmoc-(R)-3-Amino-4-(3,4-difluorophenyl)butyric acid from NINGBO INNO PHARMCHEM CO.”