Hexahydroisonicotinamide: A Key Intermediate for Pharmaceutical Innovation
The pharmaceutical industry's progress hinges on the availability of specialized chemical compounds that act as building blocks for new medicines. Hexahydroisonicotinamide, identified by CAS number 39546-32-2, is one such vital intermediate. Known also by its synonyms such as isonipecotamide or 4-piperidinecarboxamide, this white crystalline powder is instrumental in the synthesis of a wide range of pharmaceutical agents, driving innovation in drug discovery and development.
With a melting point of 145-148°C and good solubility in water, Hexahydroisonicotinamide offers chemists a reliable and adaptable starting material. Its primary role in the pharmaceutical sector is as a versatile reactant for creating complex drug molecules. It is crucial for the synthesis of Survival Motor Neuron (SMN) protein modulators, which target specific pathways involved in neurological health. The compound is also employed in the development of orally available naphthyridine protein kinase D inhibitors, a class of drugs with significant therapeutic potential across various disease areas. The consistent demand for buy Hexahydroisonicotinamide reflects its indispensable nature in medicinal chemistry.
Furthermore, Hexahydroisonicotinamide is utilized in the production of heteroalicyclic carboxamidines that function as inhibitors of inducible nitric oxide synthase, thereby aiding in the development of anti-inflammatory treatments. Its application extends to the synthesis of phosphodiesterase 5 inhibitors, crucial for treating conditions like erectile dysfunction. The efficiency of isonipecotamide synthesis is critical for supplying the pharmaceutical industry with this key intermediate. Companies looking for a trusted source of Hexahydroisonicotinamide manufacturers often prioritize purity and consistent supply.
Beyond its direct role in API synthesis, the compound also serves as a fluorenylmethyloxycarbonyl-deprotection agent in organic synthesis. This capability streamlines complex chemical reactions, making it easier to manipulate and modify molecular structures. Researchers and chemical suppliers recognize the importance of accessing reliable sources for CAS 39546-32-2. The ability to buy Hexahydroisonicotinamide online provides accessibility for a global research community.
In conclusion, Hexahydroisonicotinamide is a pivotal compound in the pharmaceutical innovation landscape. Its broad synthetic utility, combined with its well-established chemical properties, makes it an indispensable intermediate for developing next-generation therapeutics. Its continued application in diverse drug synthesis pathways solidifies its position as a critical component for the advancement of medicinal chemistry and patient care.
Perspectives & Insights
Logic Thinker AI
“The compound is also employed in the development of orally available naphthyridine protein kinase D inhibitors, a class of drugs with significant therapeutic potential across various disease areas.”
Molecule Spark 2025
“The consistent demand for buy Hexahydroisonicotinamide reflects its indispensable nature in medicinal chemistry.”
Alpha Pioneer 01
“Furthermore, Hexahydroisonicotinamide is utilized in the production of heteroalicyclic carboxamidines that function as inhibitors of inducible nitric oxide synthase, thereby aiding in the development of anti-inflammatory treatments.”