Hexahydroisonicotinamide (CAS: 39546-32-2): Your Partner in Pharmaceutical Intermediates
In the competitive pharmaceutical research and development sector, securing reliable access to high-quality intermediates is non-negotiable. Hexahydroisonicotinamide, bearing the CAS number 39546-32-2, has emerged as a compound of significant importance. Often referred to as isonipecotamide or 4-piperidinecarboxamide, this white crystalline powder is a fundamental building block in the synthesis of a wide array of advanced pharmaceutical compounds, thereby playing a crucial role in the journey of bringing novel therapies to fruition.
The compound's properties, including a melting point of 145-148°C and good solubility in water, make it exceptionally useful for complex organic synthesis. Its primary value in the pharmaceutical industry is as a versatile intermediate. It is a key reactant for the synthesis of critical drug candidates such as Survival Motor Neuron (SMN) protein modulators, which are pivotal for developing treatments for specific neurological conditions. The development of orally available naphthyridine protein kinase D inhibitors also relies on this compound, enhancing the convenience and effectiveness of drug administration.
Furthermore, Hexahydroisonicotinamide is employed in the creation of heteroalicyclic carboxamidines that inhibit inducible nitric oxide synthase, contributing to advancements in anti-inflammatory drug development. Its role in synthesizing phosphodiesterase 5 inhibitors, used for treating conditions like erectile dysfunction, further underscores its therapeutic relevance. The efficiency and purity achieved through proper isonipecotamide synthesis are critical factors for its widespread adoption. Therefore, researchers actively look for reputable Hexahydroisonicotinamide manufacturers.
The compound also serves a vital function in organic chemistry as a fluorenylmethyloxycarbonyl (Fmoc) deprotection agent. This capability streamlines complex synthetic procedures, facilitating the precise manipulation of molecular structures and improving overall reaction yields. The ability to buy Hexahydroisonicotinamide CAS 39546-32-2 from trusted suppliers is essential for reproducible scientific outcomes. Many researchers choose to buy Hexahydroisonicotinamide online to ensure timely access to this crucial reagent.
In essence, Hexahydroisonicotinamide is an indispensable component in the modern pharmaceutical intermediate market. Its broad synthetic applicability and established chemical profile make it a go-to compound for creating innovative drug molecules. For any organization engaged in pharmaceutical R&D, understanding and securing a supply of this intermediate is a strategic advantage in the pursuit of groundbreaking therapeutic solutions.
Perspectives & Insights
Molecule Vision 7
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