The development of targeted cancer therapies has revolutionized medicine, offering more effective and often less toxic treatment options for patients. Central to these advancements is the precise synthesis of complex drug molecules. (2R)-2-Chlorobutanoic Acid, with its CAS number 54053-45-1, emerges as a pivotal intermediate in the synthesis of Idelalisib, a significant drug used in treating certain B-cell malignancies like chronic lymphocytic leukemia (CLL). NINGBO INNO PHARMCHEM CO., LTD. is a prime supplier of this essential chemical precursor.

Idelalisib (brand name Zydelig®) functions as a PI3Kδ inhibitor, effectively targeting signaling pathways crucial for the survival and proliferation of cancerous B cells. The efficacy and safety of Idelalisib are intrinsically linked to its stereochemical purity. This is where (2R)-2-Chlorobutanoic Acid plays its critical role. As a chiral building block, it introduces a specific stereocenter into the Idelalisib molecule during its multi-step synthesis. The '(2R)' configuration is not arbitrary; it is specifically required for the drug to correctly bind to its target enzyme and exert its therapeutic effect. Therefore, manufacturers of Idelalisib rely heavily on the consistent availability of high-purity (2R)-2-chlorobutanoic acid to ensure the quality and effectiveness of the final pharmaceutical product.

The chemical industry, particularly manufacturers in China, has developed sophisticated capabilities in producing enantiomerically pure intermediates like (2R)-2-Chlorobutanoic Acid. NINGBO INNO PHARMCHEM CO., LTD. exemplifies this, offering a product with an assay of ≥98.0%, meeting the exacting standards of pharmaceutical synthesis. Their ability to provide this compound in various quantities, from kilograms for research and development to tons for commercial production, makes them a valuable partner for drug manufacturers. When companies look to buy (2R)-2-chlorobutanoic acid for Idelalisib production or similar projects, partnering with a reliable supplier like NINGBO INNO PHARMCHEM CO., LTD. is key to maintaining production timelines and product integrity.

Beyond its role in Idelalisib, the inherent chemical reactivity and chirality of (2R)-2-Chlorobutanoic Acid make it a versatile intermediate for various other organic synthesis applications. It can be employed in the creation of agrochemicals, other pharmaceutical compounds, and novel materials where precise stereochemistry is a design consideration. The ability to source such a versatile intermediate efficiently and cost-effectively from established manufacturers in China, like NINGBO INNO PHARMCHEM CO., LTD., significantly aids innovation across multiple scientific and industrial sectors. Understanding the market price for 2-Chlorobutanoic acid and its associated suppliers is a crucial step for any organization planning their procurement strategy.

In conclusion, the synthesis of advanced pharmaceuticals like Idelalisib highlights the indispensable nature of high-quality chiral intermediates. (2R)-2-Chlorobutanoic Acid, supplied reliably by NINGBO INNO PHARMCHEM CO., LTD., is a prime example of such a critical component. Its precise stereochemistry is not just a chemical detail but a fundamental requirement for therapeutic efficacy, underscoring the importance of specialized chemical manufacturing for modern healthcare.