The field of organic synthesis is constantly evolving, driven by the demand for novel molecules with significant biological activity. Pyrazolo[3,4-d]pyrimidine derivatives represent a class of heterocyclic compounds that have garnered considerable attention due to their diverse pharmacological properties. At the forefront of this class is (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1022150-12-4), a crucial intermediate that exemplifies the potential of this chemical scaffold.

NINGBO INNO PHARMCHEM CO.,LTD. recognizes the integral role that such research chemicals play in driving innovation. This particular compound is a key component in the synthesis of Ibrutinib, a successful Bruton's tyrosine kinase (Btk) inhibitor. The development of Ibrutinib showcases the power of targeted molecular design, where a specific chemical intermediate serves as the foundation for a life-changing drug. The success of Ibrutinib intermediate synthesis highlights the importance of advancements in synthetic methodologies.

Beyond its direct application in Ibrutinib, the structural framework of this pyrazolo-pyrimidine derivative offers broad potential for developing new therapies. Researchers are actively exploring its use as a Bruton's tyrosine kinase inhibitor precursor and investigating modifications that could lead to inhibitors for other kinases implicated in various diseases. This versatility makes it a highly sought-after fine chemical for pharmaceutical R&D.

The intricate chemical synthesis required to produce high-purity compounds like (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, with its specific stereochemistry and molecular weight of 386.45, pushes the boundaries of synthetic organic chemistry. Efficient and scalable routes are continuously being developed, improving accessibility and reducing costs for critical API intermediate sourcing. NINGBO INNO PHARMCHEM CO.,LTD. is committed to contributing to these synthetic advancements.

In essence, the exploration and application of pyrazolo[3,4-d]pyrimidine derivatives, exemplified by the detailed study and supply of (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, are critical for the continued progress in medicinal chemistry and drug discovery. NINGBO INNO PHARMCHEM CO.,LTD. remains at the forefront, supporting the development of next-generation therapeutics through the provision of high-quality chemical building blocks.