The Science Behind Isoconazole Nitrate: A Deep Dive into its Chemical Properties
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing comprehensive information about the chemical compounds we supply. Today, we focus on Isoconazole Nitrate, delving into its chemical properties and the science that underpins its effectiveness as a potent antifungal agent.
Isoconazole Nitrate, with the CAS number 24168-96-5, is a synthetic imidazole derivative. Its chemical structure is key to its biological activity. The compound contains a chlorinated phenyl group and a chlorinated benzyl group attached to an ethyl-imidazole core, with a nitrate salt forming part of its structure. This complex arrangement of atoms and functional groups dictates its interaction with fungal cells.
The core of Isoconazole Nitrate's efficacy lies in its isoconazole nitrate mechanism of action. As an azole antifungal, it inhibits the cytochrome P450-dependent enzyme lanosterol 14α-demethylase. This enzyme is critical in the biosynthesis pathway of ergosterol, the primary sterol component of fungal cell membranes. By blocking ergosterol synthesis, Isoconazole Nitrate disrupts the structural integrity and fluidity of the fungal cell membrane. This leads to an accumulation of toxic intermediate sterols and the eventual death of the fungal cell.
Understanding these chemical properties is essential for appreciating its diverse isoconazole nitrate uses. In pharmaceuticals, its lipophilic nature allows for good penetration into skin tissues, making it effective for topical treatments of fungal infections. In agriculture, its stability and efficacy against common plant pathogens like powdery mildew are attributed to its robust chemical structure.
For those looking to buy Isoconazole Nitrate, it's important to consider the purity and specifications provided by the manufacturer. NINGBO INNO PHARMCHEM CO.,LTD. offers Isoconazole Nitrate with high purity levels, essential for both pharmaceutical intermediates and specialized agricultural applications. The isoconazole nitrate price is reflective of these stringent quality controls and the complex synthesis process involved.
The chemical characteristics of Isoconazole Nitrate, from its molecular structure to its reactive functional groups, are precisely what make it such a powerful agent against fungal pathogens. Its consistent performance across various applications underscores the importance of chemical precision in product development. NINGBO INNO PHARMCHEM CO.,LTD. is proud to supply this scientifically significant compound to support innovation and research worldwide.
Perspectives & Insights
Alpha Spark Labs
“The core of Isoconazole Nitrate's efficacy lies in its isoconazole nitrate mechanism of action.”
Future Pioneer 88
“As an azole antifungal, it inhibits the cytochrome P450-dependent enzyme lanosterol 14α-demethylase.”
Core Explorer Pro
“This enzyme is critical in the biosynthesis pathway of ergosterol, the primary sterol component of fungal cell membranes.”