4-Amino-5-ethylsulfonyl-2-methoxybenzoic acid, identified by CAS number 71675-87-1, is a significant compound within the fine chemical and pharmaceutical industries. Its importance stems largely from its role as a key intermediate in the synthesis of amisulpride, an widely used atypical antipsychotic medication. Understanding its core characteristics and applications is crucial for professionals involved in chemical sourcing and pharmaceutical development.

Physically, this compound typically presents as a white to off-white powder. Its melting point is generally reported to be in the range of 82-85°C, which is a key parameter for its identification and quality assessment. In terms of solubility, it exhibits slight solubility in organic solvents such as chloroform and methanol, while its water solubility is relatively low, around 8.555 g/L at 25°C. These solubility profiles influence the choice of solvents and conditions used during its synthesis and subsequent reactions.

The chemical structure of 4-Amino-5-ethylsulfonyl-2-methoxybenzoic acid features an amino group, an ethylsulfonyl group, a methoxy group, and a carboxylic acid group attached to a benzene ring. This arrangement of functional groups provides the reactivity necessary for its transformation into more complex molecules like amisulpride. The precise chemical properties of 4-Amino-5-ethylsulfonyl-2-methoxybenzoic acid are therefore directly linked to its utility in organic synthesis.

The primary application of this compound is its use as an intermediate in the manufacturing of amisulpride. It is also recognized as Amisulpride EP Impurity E, indicating its relevance in pharmaceutical quality control and regulatory compliance. As a critical component for API synthesis, ensuring the availability of high-purity material through reliable 4-Amino-5-ethylsulfonyl-2-methoxybenzoic acid suppliers is paramount for drug manufacturers. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are key players in providing this essential chemical.

Effective handling and storage of 4-Amino-5-ethylsulfonyl-2-methoxybenzoic acid are also important considerations. Typically, it should be stored in a cool, dry, and well-closed container, protected from moisture and strong light or heat, to maintain its stability and purity.

In summary, 4-Amino-5-ethylsulfonyl-2-methoxybenzoic acid is a compound defined by its powdery appearance, specific melting point, and crucial role as a pharmaceutical intermediate, particularly in the synthesis of amisulpride. Its consistent availability from reputable suppliers is vital for the pharmaceutical industry.