NINGBO INNO PHARMCHEM CO.,LTD. is pleased to offer comprehensive information on essential chemical intermediates that are vital for the advancement of pharmaceutical therapies. Today, we focus on 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride (CAS 256499-19-1), a cornerstone in the production of Riociguat. Riociguat is a critical medication used in the treatment of pulmonary hypertension, a condition that severely affects the vascular system of the lungs.

The therapeutic efficacy of Riociguat stems from its ability to directly stimulate soluble guanylate cyclase (sGC), promoting vasodilation and reducing pulmonary artery pressure. The synthesis of such a potent drug requires intermediates of exceptional quality and purity. Our 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride, featuring an assay of u226598.0% and a consistent white solid appearance, is engineered to meet these stringent demands, ensuring the integrity of the Riociguat intermediate synthesis process.

As a premier pharmaceutical intermediate manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. understands the critical need for reliable supply chains. When organizations choose to buy 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride, they are partnering with a company dedicated to quality and precision. This commitment is essential for the efficient chemical synthesis of Riociguat and the subsequent availability of this important medication.

The chemical family of pyrazolo[3,4-b]pyridine derivatives is a highly active area of research in medicinal chemistry, with many compounds exhibiting significant therapeutic potential. Our intermediate is a prime example, serving as a direct precursor for a drug that has made a substantial impact on pulmonary hypertension treatment. The complexity of Riociguat intermediate synthesis highlights the advanced capabilities required in the specialty chemical sector.

NINGBO INNO PHARMCHEM CO.,LTD. is proud to contribute to global health by supplying essential chemical building blocks. Our dedication to producing high-quality CAS 256499-19-1 ensures that pharmaceutical companies can effectively manufacture treatments for pulmonary hypertension. We are committed to being a trusted partner in the pharmaceutical industry's pursuit of innovative healthcare solutions.

In essence, 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride is a vital element in the synthesis of Riociguat, directly enhancing the treatment of pulmonary hypertension. NINGBO INNO PHARMCHEM CO.,LTD. remains at the forefront of supplying these critical intermediates, driving progress in pharmaceutical science.