For chemists engaged in the intricate art of organic synthesis, the selection of appropriate reagents and intermediates is crucial for success. NINGBO INNO PHARMCHEM CO.,LTD. presents this guide to 4-Amino-3,5-dichlorophenacyl bromide (CAS: 37148-47-3), a versatile compound widely used in the preparation of fine chemicals and complex organic molecules. Understanding its characteristics and reactivity will empower chemists to unlock its full potential in their research and development endeavors.

The compound, appearing as a yellow solid, possesses the molecular formula C8H6BrCl2NO and a molecular weight of 282.95. Its melting point of 145ºC indicates its solid state at room temperature, and it is generally stable under typical laboratory conditions. The presence of the alpha-bromo ketone functionality is key to its reactivity. This electrophilic center is susceptible to nucleophilic attack, making it an excellent precursor for forming new carbon-carbon and carbon-heteroatom bonds. This reactivity is central to its utility in various organic synthesis applications.

In the realm of fine chemical preparation, 4-Amino-3,5-dichlorophenacyl bromide serves as a valuable building block. Its structure allows for further modifications through reactions such as nucleophilic substitution at the alpha-carbon, amide formation with the amino group, or reactions involving the aromatic ring. These transformations enable the synthesis of a wide array of complex organic structures, including potential pharmaceutical agents and specialty chemicals. Chemists can leverage this intermediate to introduce specific functionalities or to build larger molecular frameworks efficiently.

The pharmaceutical intermediate synthesis sector heavily relies on compounds like 4-Amino-3,5-dichlorophenacyl bromide. Its structure is amenable to further derivatization, leading to molecules with tailored biological activities. For instance, it can be a precursor in the synthesis of beta-agonists or other therapeutic agents where the specific arrangement of functional groups is critical. NINGBO INNO PHARMCHEM CO.,LTD. ensures that its supply of this intermediate meets high-purity standards, which is non-negotiable for sensitive pharmaceutical synthesis. Access to reliable sources for such compounds is vital for driving innovation in drug development.

Furthermore, when planning synthetic routes, chemists often consider the availability and cost-effectiveness of intermediates. 4-Amino-3,5-dichlorophenacyl bromide, with its established synthesis and commercial availability, presents a practical option for many projects. The compound's unique combination of functionalities makes it a strategic choice for researchers aiming to create novel molecular architectures efficiently. Exploring different reaction conditions and strategies with this reagent can lead to unexpected and valuable synthetic outcomes. Chemists are encouraged to consult detailed reaction protocols and safety data sheets when working with this chemical.

In summary, mastering the use of 4-Amino-3,5-dichlorophenacyl bromide in organic synthesis opens up numerous possibilities for chemists. Its versatile reactivity, coupled with its role as a key building block, makes it an indispensable component in the creation of fine chemicals and pharmaceuticals. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting the chemical community by providing high-quality materials that facilitate groundbreaking research and development.