At NINGBO INNO PHARMCHEM CO.,LTD., we understand that selecting the right grade of Microcrystalline Cellulose (MCC) is crucial for optimizing pharmaceutical formulations. While both PH 101 and PH 102 are widely used and highly effective, they possess distinct characteristics that make them suitable for different applications.

The primary difference between MCC PH 101 and MCC PH 102 lies in their particle size and, consequently, their bulk density. MCC PH 101 typically has a finer particle size, with a lower bulk density. This finer particle size can contribute to excellent compressibility, making it a preferred choice for certain direct compression applications where very high tablet strength is required or for formulations involving very fine APIs.

MCC PH 102, on the other hand, features a slightly larger average particle size. This leads to a marginally higher bulk density compared to PH 101. The larger particle size of PH 102 generally results in improved powder flow characteristics. This enhanced flow is particularly advantageous in high-speed tableting and capsule filling operations, where consistent die filling and accurate dosage are paramount. Many formulators find PH 102 to be the preferred grade for general-purpose direct compression and wet granulation due to this balance of compressibility and flowability.

Both grades offer excellent binding capabilities, act as effective diluents, and contribute to tablet disintegration. The choice between PH 101 and PH 102 often depends on specific formulation challenges, such as the flow properties of the API, the desired tablet hardness, and the manufacturing equipment being used.

For formulators seeking optimal processing efficiency and reliable tablet performance, understanding these subtle differences is key. NINGBO INNO PHARMCHEM CO.,LTD. supplies both high-quality MCC PH 101 and MCC PH 102, providing the essential ingredients for successful pharmaceutical development. We recommend consulting technical data sheets and considering your specific formulation requirements when making your selection.