Methyl 3-Bromo-4-fluorobenzoate: A Key Component in Modern Drug Discovery
The journey from a concept to a viable drug is a complex and intricate process, heavily reliant on the availability of precise and high-quality chemical intermediates. At NINGBO INNO PHARMCHEM CO.,LTD., we understand this critical need and are dedicated to supplying essential compounds like Methyl 3-Bromo-4-fluorobenzoate (CAS: 82702-31-6). This compound serves as a foundational building block, playing a pivotal role in the synthesis of numerous active pharmaceutical ingredients (APIs) that form the basis of new medicines.
Methyl 3-Bromo-4-fluorobenzoate is prized for its strategic molecular design. It features a methyl ester group, a bromine atom, and a fluorine atom appended to a benzene ring. This combination offers a rich landscape for chemical transformations. The bromine atom is particularly valuable for its participation in various palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction. These reactions are indispensable for constructing complex carbon-carbon bonds, allowing medicinal chemists to assemble sophisticated molecular architectures that are key to drug efficacy. By employing these coupling strategies, researchers can efficiently introduce diverse functional groups and extend molecular frameworks, tailoring compounds for specific biological targets.
The presence of fluorine in organic molecules, including those synthesized from Methyl 3-Bromo-4-fluorobenzoate, is a recurring theme in successful drug discovery. Fluorine substitution can favorably alter a molecule's properties in several ways. It often enhances metabolic stability by blocking sites susceptible to enzymatic degradation, thereby prolonging the drug's action in the body. Furthermore, fluorine can increase lipophilicity, which aids in crossing biological membranes, and can also modulate binding affinity to target receptors. This makes fluorinated intermediates like Methyl 3-Bromo-4-fluorobenzoate exceptionally valuable in the drug discovery pipeline.
As prominent pharmaceutical intermediates suppliers, NINGBO INNO PHARMCHEM CO.,LTD. ensures that when you buy Methyl 3-Bromo-4-fluorobenzoate, you receive a product of exceptional purity and consistency. High-quality intermediates are crucial for the successful methyl 3-bromo-4-fluorobenzoate synthesis and ensure that the subsequent steps in drug development proceed smoothly, without the complications of side reactions or purification challenges caused by impurities.
The broad 3-bromo-4-fluorobenzoic acid methyl ester uses extend across various therapeutic areas. Researchers leverage its structure to create novel agents for oncology, infectious diseases, cardiovascular conditions, and neurological disorders, among others. By providing this vital intermediate, NINGBO INNO PHARMCHEM CO.,LTD. actively supports the global effort to develop new and improved treatments. Partner with us for your chemical needs and let us be a part of your drug discovery success story.
Perspectives & Insights
Logic Thinker AI
“The presence of fluorine in organic molecules, including those synthesized from Methyl 3-Bromo-4-fluorobenzoate, is a recurring theme in successful drug discovery.”
Molecule Spark 2025
“Fluorine substitution can favorably alter a molecule's properties in several ways.”
Alpha Pioneer 01
“It often enhances metabolic stability by blocking sites susceptible to enzymatic degradation, thereby prolonging the drug's action in the body.”