Microcrystalline Cellulose 200: A Versatile Excipient for Wet and Dry Granulation by NINGBO INNO PHARMCHEM CO.,LTD.
In pharmaceutical manufacturing, granulation is a common step to improve powder flow and compressibility. Microcrystalline Cellulose (MCC), particularly grade 200, is a highly effective excipient for both wet and dry granulation processes, and NINGBO INNO PHARMCHEM CO.,LTD. is a trusted provider of this essential material. MCC 200's unique properties make it an ideal choice for formulators aiming to optimize their tablet production.
For wet granulation, MCC 200's superior fluidity and particle characteristics allow for even distribution of the granulating fluid. This leads to the formation of uniform granules, which in turn ensures consistency in drying and subsequent compression. The ability of MCC 200 to act as a binder during wet granulation is crucial for creating robust granules that maintain their integrity. Pharmaceutical companies looking to purchase MCC for granulation processes often choose grade 200 for its reliable performance and the predictable outcomes it offers.
In dry granulation, also known as roller compaction, MCC 200 performs exceptionally well. It forms strong ribbons during the compaction stage, which then yield granules with excellent flow and compressibility. This bypasses the need for moisture, making it suitable for moisture-sensitive active pharmaceutical ingredients (APIs). The advantages of using MCC 200 in dry granulation are clear: it simplifies the process, reduces manufacturing time, and enhances the quality of the final product. The price of MCC 200 is competitive when considering the overall efficiency it brings to dry granulation.
NINGBO INNO PHARMCHEM CO.,LTD. understands the critical role of MCC 200 in achieving desired tablet properties. As a binder, it imparts strength; as a disintegrant, it aids in drug release; and as a diluent, it provides necessary bulk. Its versatility across granulation methods underscores its importance. Manufacturers seeking to buy MCC often rely on NINGBO INNO PHARMCHEM CO.,LTD. for consistent quality and supply, knowing that their formulations will benefit from the superior characteristics of MCC 200.
The strategic selection of MCC 200 from NINGBO INNO PHARMCHEM CO.,LTD. can significantly improve tablet hardness, reduce friability, and ensure good content uniformity. For companies aiming for efficient and high-quality tablet production, MCC 200 is an indispensable pharmaceutical ingredient that supports both wet and dry granulation techniques, delivering tangible benefits in terms of performance and cost-effectiveness.
Perspectives & Insights
Agile Reader One
“Microcrystalline Cellulose (MCC), particularly grade 200, is a highly effective excipient for both wet and dry granulation processes, and NINGBO INNO PHARMCHEM CO.”
Logic Vision Labs
“MCC 200's unique properties make it an ideal choice for formulators aiming to optimize their tablet production.”
Molecule Origin 88
“For wet granulation, MCC 200's superior fluidity and particle characteristics allow for even distribution of the granulating fluid.”