The field of drug discovery is continually seeking innovative and efficient methods to synthesize complex molecules with precise stereochemistry. In this pursuit, chiral building blocks play an indispensable role, and N-Boc-D-phenylalaninol, identified by its CAS number 106454-69-7, stands out as a particularly valuable compound. Its unique structural features and the presence of a protective group make it a crucial intermediate in various synthetic pathways, especially those aimed at developing chiral drugs.

N-Boc-D-phenylalaninol is a derivative of the amino acid D-phenylalanine, functionalized with a tert-butyloxycarbonyl (Boc) protecting group. This Boc protection is a standard and highly effective strategy in organic synthesis for temporarily masking reactive amine groups. This masking allows chemists to selectively modify other parts of the molecule without interference, thereby simplifying complex multi-step syntheses. The resultant compound is typically a white to light yellow crystalline powder with good stability under recommended storage conditions (2-8°C). Its specific rotation, +24°(23℃, c=1, CHCl3), confirms its specific chirality, a trait highly prized in pharmaceutical synthesis.

The significance of N-Boc-D-phenylalaninol as a chiral building block cannot be overstated. In the development of pharmaceuticals, the stereochemistry of a molecule can dramatically influence its biological activity, efficacy, and safety profile. Compounds that are enantiomerically pure or enriched are often required to target specific biological pathways effectively and minimize off-target effects. N-Boc-D-phenylalaninol provides a reliable means to introduce a specific chiral center into target molecules, aiding in the synthesis of enantiomerically pure drug candidates. Its use as an intermediate in the preparation of (S)-Amphetamine is a well-known example of its application in synthesizing stereochemically defined compounds.

Beyond its role in specific syntheses, N-Boc-D-phenylalaninol finds application as a versatile intermediate in broader organic synthesis. Researchers utilize it to construct intricate molecular architectures, explore new reaction methodologies, and synthesize libraries of compounds for screening in drug discovery programs. The reliability and purity of this compound, often exceeding 95%, make it a preferred choice for demanding research environments where consistent results are paramount.

Ningbo Inno Pharmchem Co., Ltd. is a trusted provider of specialized chemical intermediates, including N-Boc-D-phenylalaninol. By understanding the critical need for high-quality pharmaceutical intermediates, they ensure that their products meet stringent specifications. For scientists and manufacturers looking to buy N-Boc-D-phenylalaninol, partnering with reputable suppliers like Ningbo Inno Pharmchem Co., Ltd. is essential for the success of their research and development endeavors. Their commitment to quality supports the advancement of organic synthesis building blocks research.

In essence, N-Boc-D-phenylalaninol (CAS: 106454-69-7) serves as a critical component in the toolkit of modern medicinal chemists. Its utility as a chiral building block, combined with the strategic advantage of Boc protection, makes it an invaluable asset in the ongoing efforts of drug discovery and the development of innovative therapeutic solutions.