Phloroglucinol, identified by its CAS number 108-73-6, is a fascinating organic compound whose chemical structure dictates its wide-ranging applications. Understanding its properties and how it is synthesized provides valuable insight into its industrial importance.

Chemically, phloroglucinol is a benzenetriol, meaning it is a benzene ring with three hydroxyl (-OH) groups attached. Its molecular formula is C6H6O3. These hydroxyl groups impart several key properties: it is a weak triprotic acid, and it exhibits tautomerism, existing in equilibrium between its enol and keto forms. Spectroscopic evidence suggests that while the enol form is predominant in neutral compounds, the keto tautomer becomes more significant upon deprotonation.

Phloroglucinol is a colorless to beige solid, typically appearing as a white or light yellow crystalline powder. It is soluble in water, ethanol, and pyridine, which facilitates its use in various aqueous and organic solvent systems. Its melting point is notably high, around 215-219°C for the pure product, indicating strong intermolecular forces within its crystal lattice.

The synthesis of phloroglucinol can be achieved through several pathways. Historically, it was first prepared from phloretin. Modern synthesis methods often involve the hydrolysis of benzene-1,3,5-triamine or its derivatives. For instance, a route from trinitrobenzene is employed, which is notable given the usual unreactivity of ordinary aniline derivatives towards hydroxide. The triaminobenzene's tautomerism to its imine form makes it susceptible to hydrolysis, enabling the formation of phloroglucinol.

For industries relying on high-purity phloroglucinol, such as pharmaceutical manufacturers and research institutions, understanding the phloroglucinol chemical name and its synthesis is crucial. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing products that meet stringent phloroglucinol quality standard 99% requirements, reflecting the advanced synthesis and purification processes we employ.

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