Understanding the Properties and Applications of (R)-1-Boc-3-Aminopyrrolidine (CAS 147081-49-0)
NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing high-quality chemical intermediates, and (R)-1-Boc-3-Aminopyrrolidine (CAS 147081-49-0) is a prime example of our commitment to excellence. This compound is a colorless to light yellow liquid with a molecular formula of C9H18N2O2 and a molecular weight of 186.25. Understanding its properties is key to leveraging its full potential in research and manufacturing.
The chemical and physical characteristics of (R)-1-Boc-3-Aminopyrrolidine make it a sought-after intermediate. It exhibits a density of approximately 1.098 g/cm³ and a refractive index of 1.4720, which are important parameters for quality control during production and application. While the provided material mentions a boiling point around 243.244ºC, other sources note a boiling point of 95-98 °C at 5 mm Hg, indicating its behavior under different pressure conditions. Its purity, typically ≥97%, is crucial for its use in sensitive pharmaceutical synthesis, where even trace impurities can affect the final product's efficacy and safety.
The Boc (tert-butyloxycarbonyl) protecting group on the amine functionality of the pyrrolidine ring provides enhanced stability and facilitates specific chemical reactions. This feature is particularly advantageous in complex multi-step syntheses, allowing chemists to selectively modify other parts of the molecule without affecting the protected amine. This makes (R)-1-Boc-3-Aminopyrrolidine an essential component in the synthesis of chiral drugs, including its well-documented role as a Linagliptin intermediate. Pharmaceutical companies looking to buy (R)-1-Boc-3-Aminopyrrolidine for such critical applications rely on its consistent quality from NINGBO INNO PHARMCHEM CO.,LTD.
The applications of this compound extend beyond its primary use as a pharmaceutical intermediate. It is a valuable tool in general organic synthesis, enabling the creation of a wide array of complex organic molecules. Furthermore, its chiral nature makes it indispensable in asymmetric synthesis, where the specific spatial arrangement of atoms is paramount for biological activity. Researchers in biochemical fields also utilize it to understand enzyme functions and protein structures.
NINGBO INNO PHARMCHEM CO.,LTD. ensures that our supply of (R)-1-Boc-3-Aminopyrrolidine adheres to the highest standards. We understand the importance of precise specifications for our clients in the pharmaceutical, agrochemical, and fine chemical industries. For further details on product specifications, availability, or to place an order, please contact our sales team. We are committed to supporting your success with reliable chemical intermediates.
Perspectives & Insights
Logic Thinker AI
“It is a valuable tool in general organic synthesis, enabling the creation of a wide array of complex organic molecules.”
Molecule Spark 2025
“Furthermore, its chiral nature makes it indispensable in asymmetric synthesis, where the specific spatial arrangement of atoms is paramount for biological activity.”
Alpha Pioneer 01
“Researchers in biochemical fields also utilize it to understand enzyme functions and protein structures.”