The Role of Protected Histidine in Peptide Synthesis: A Focus on Boc-His(Trt)-OH by NINGBO INNO PHARMCHEM CO.,LTD.
NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of high-quality chemical compounds essential for scientific research and industrial applications, with a particular focus on peptide synthesis.
The amino acid histidine presents unique challenges in peptide synthesis due to its imidazole ring, which can undergo various side reactions. To overcome this, chemists employ protected histidine derivatives. Boc-His(Trt)-OH (CAS 32926-43-5), also known as N-alpha-Boc-N-tau-trityl-L-histidine, is a widely used and highly effective protected form. The tert-butoxycarbonyl (Boc) group protects the alpha-amino group, ensuring controlled chain extension, while the trityl (Trt) group safeguards the imidazole nitrogen. This dual protection is critical for the successful synthesis of complex peptide sequences.
The importance of this protected histidine derivative for peptide synthesis cannot be overstated. It is a key component in the toolkit for both solid-phase and solution-phase peptide synthesis. Researchers often investigate the price of Boc-His(Trt)-OH to manage their project costs, and NINGBO INNO PHARMCHEM CO.,LTD. strives to offer competitive pricing for this essential reagent. The ability to reliably buy Boc-His(Trt)-OH ensures that synthesis projects can proceed without interruption.
The process of Boc-L-Histidine(Trt) preparation is optimized to yield a product of high purity and stability. This meticulous preparation is vital for ensuring the success of subsequent peptide synthesis reagents Boc-His(Trt)-OH applications. By providing access to this derivative, NINGBO INNO PHARMCHEM CO.,LTD. empowers researchers to synthesize peptides with precise structures and desired biological activities. The detailed understanding of Boc-His(Trt)-OH CAS 32926-43-5 synthesis by manufacturers and users alike contributes to the overall efficiency of peptide production.
Furthermore, this derivative serves as a critical chemical intermediate Boc-His(Trt)-OH in the development of peptide-based pharmaceuticals. Its protected nature allows for controlled incorporation into therapeutic peptides, contributing to the creation of novel drugs with improved efficacy and reduced side effects. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting these advancements by providing reliable access to such vital chemical components.
In essence, Boc-His(Trt)-OH is a cornerstone in modern peptide chemistry, and NINGBO INNO PHARMCHEM CO.,LTD. is a trusted partner in its supply, facilitating scientific discovery and pharmaceutical innovation.
Perspectives & Insights
Molecule Vision 7
“The amino acid histidine presents unique challenges in peptide synthesis due to its imidazole ring, which can undergo various side reactions.”
Alpha Origin 24
“Boc-His(Trt)-OH (CAS 32926-43-5), also known as N-alpha-Boc-N-tau-trityl-L-histidine, is a widely used and highly effective protected form.”
Future Analyst X
“The tert-butoxycarbonyl (Boc) group protects the alpha-amino group, ensuring controlled chain extension, while the trityl (Trt) group safeguards the imidazole nitrogen.”