At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to supplying cutting-edge biochemicals that facilitate breakthroughs in life sciences. AM2394 (CAS: 1442684-77-6) is one such compound, recognized for its remarkable ability to activate glucokinase. This activation is fundamental to maintaining healthy blood sugar levels, making AM2394 a vital resource for researchers studying carbohydrate metabolism and diabetes.

The core function of AM2394 lies in its potent glucokinase activating properties. Glucokinase, a key enzyme in glucose metabolism, controls the rate-limiting step of glucose phosphorylation. By increasing the affinity of glucokinase for glucose, AM2394 enhances the enzyme's efficiency, particularly at physiological glucose concentrations. This mechanism is crucial for proper insulin secretion and glucose uptake by various tissues. The precise EC50 of 60 nM for AM2394 underscores its high potency in achieving this effect, a key factor for researchers looking to buy AM2394 for precise experimental control.

The pharmacokinetic profile of AM2394 further enhances its utility. Exhibiting good oral bioavailability, this compound is readily absorbed and distributed within the body, making it suitable for in vivo studies. Its ability to effectively lower plasma glucose levels during oral glucose tolerance tests in animal models of diabetes showcases its therapeutic promise. Researchers can rely on AM2394 as a reliable tool to explore strategies for managing hyperglycemia, a hallmark of diabetes. The consistent quality provided by NINGBO INNO PHARMCHEM CO.,LTD. ensures that the observed effects are attributable to the compound's inherent properties.

As a leading supplier of pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. understands the importance of high-purity compounds for reproducible research. AM2394 is supplied with rigorous quality control, ensuring its suitability for complex biochemical assays and preclinical studies. Its application in understanding glucose regulation and its potential role in developing novel antidiabetic therapies make it a significant compound in the scientific community. The availability of AM2394 at a competitive price point enables broader access to this essential research chemical.

In conclusion, AM2394 represents a significant advancement in the field of metabolic research. Its potent glucokinase activation and favorable pharmacokinetic properties offer researchers a powerful tool to investigate blood sugar control mechanisms and explore new avenues for diabetes treatment. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting scientific progress by providing high-quality AM2394, empowering researchers to achieve their study objectives and contribute to the fight against metabolic diseases.