NINGBO INNO PHARMCHEM CO.,LTD. is proud to supply essential biochemical reagents that form the backbone of critical medical diagnostic procedures. Among these is Glutamic Acid 5-(3-Carboxy-4-Nitroanilide) Ammonium Salt (CAS 63699-78-5), a high-purity synthetic substrate that is fundamental to Gamma-Glutamyltransferase (GGT) enzyme assays.

The science behind GGT assays is elegant yet powerful. GGT is an enzyme involved in various metabolic processes, with its highest concentrations found in the liver. Elevated levels of GGT in the bloodstream are often indicative of liver damage, inflammation, or obstruction of the bile ducts. Therefore, accurately measuring GGT activity is a key diagnostic tool for hepatobiliary diseases. The process relies on a substrate that can be specifically acted upon by GGT, leading to a detectable signal.

Glutamic Acid 5-(3-Carboxy-4-Nitroanilide) Ammonium Salt serves precisely this purpose. When GGT encounters this substrate, it cleaves the molecule, releasing p-nitroaniline. This released compound has a distinct colorimetric property, allowing for its quantification using spectrophotometry. By measuring the rate at which p-nitroaniline is produced, clinicians and researchers can determine the GGT enzyme's activity in a biological sample. The compound's high purity, exceeding 99%, ensures that the signal generated is directly attributable to GGT activity, minimizing false positives or negatives.

The development and availability of such specialized pharmaceutical intermediates are crucial for the advancement of medical diagnostics. NINGBO INNO PHARMCHEM CO.,LTD. ensures that our Glutamic Acid derivative meets stringent quality standards, providing the reliability needed for accurate clinical decision-making. The enhanced solubility and stability of this substrate further contribute to the ease of use and consistency of GGT assays, making it a preferred choice for diagnostic laboratories globally.