The Science Behind Gastric and Enteric Soluble Film Coating Powders
Understanding the science behind pharmaceutical excipients is crucial for effective product development. Film coating powders, particularly those with gastric and enteric solubility, are sophisticated materials designed to optimize drug delivery. NINGBO INNO PHARMCHEM CO.,LTD. specializes in these advanced formulations, providing manufacturers with the tools they need.
The core of our gastric and enteric soluble tablet film coating powder lies in the carefully selected polymers, such as hypromellose (HPMC), cellulose acetate phthalate (CAP), and acrylic resins. These polymers exhibit pH-dependent solubility. Gastric-soluble coatings are formulated to remain intact in the stomach's acidic environment (typically pH 1.5-3.5) but to dissolve rapidly as the pH rises. Enteric-soluble coatings, on the other hand, are designed to resist the stomach's acidity and dissolve in the small intestine, where the pH is higher (typically pH 5.5 and above). This precise pH-triggered release is fundamental to targeted drug delivery, protecting acid-labile drugs or preventing gastric irritation.
The formulation also includes plasticizers, such as polyethylene glycol (PEG) or triethyl citrate, which impart flexibility to the film, preventing cracking and ensuring a continuous barrier. NINGBO INNO PHARMCHEM CO.,LTD. ensures that our powders are ready-to-use, simplifying the manufacturing process by eliminating the need for additional complex steps. Our tablet film coating powder pharma grade is produced with high coating efficiency and excellent film-forming properties, adhering to GMP and ISO 9001 standards for unwavering quality.
For applications demanding specific release profiles, the selection of the right film coating powder is non-negotiable. NINGBO INNO PHARMCHEM CO.,LTD.'s expertise in developing natural healthy tablet film coating powder, which is also BSE-free, Kosher, and Halal certified, further enhances its utility across diverse pharmaceutical and nutraceutical applications. By understanding the science behind these materials, manufacturers can confidently innovate and deliver superior products.
Perspectives & Insights
Agile Reader One
“The formulation also includes plasticizers, such as polyethylene glycol (PEG) or triethyl citrate, which impart flexibility to the film, preventing cracking and ensuring a continuous barrier.”
Logic Vision Labs
“ensures that our powders are ready-to-use, simplifying the manufacturing process by eliminating the need for additional complex steps.”
Molecule Origin 88
“Our tablet film coating powder pharma grade is produced with high coating efficiency and excellent film-forming properties, adhering to GMP and ISO 9001 standards for unwavering quality.”