The Science Behind Pharmaceutical Intermediates: A Deep Dive into N-[1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide
The chemical compound N-[1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide, identified by CAS 249289-10-9, is more than just a string of numbers and chemical names; it represents a crucial link in the sophisticated chain of modern pharmaceutical manufacturing. Primarily recognized as an intermediate or impurity in the synthesis of immunomodulatory drugs like Fingolimod, understanding its scientific profile is essential for chemists, researchers, and quality control professionals.
Scientifically, this compound is an acetamide derivative characterized by its complex structure featuring a propyl chain substituted with hydroxymethyl groups and an octylphenyl moiety. Its molecular formula, C21H35NO3, and a molecular weight of approximately 349.51 g/mol, provide fundamental identifiers. Typically presented as an off-white powder, its physical properties, such as a melting point in the range of 83-87°C, are critical for handling and process design. The specific N-[1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide properties are meticulously documented by suppliers to ensure users have accurate information for their applications.
The synthesis of such complex organic molecules presents significant scientific challenges. Achieving high purity, which is often a requirement of 99% or more for pharmaceutical intermediates, demands precise control over reaction conditions, careful selection of reagents, and effective purification techniques. The N-[1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide synthesis requires a deep understanding of organic reaction mechanisms and stereochemistry, especially if specific enantiomers are targeted. For researchers looking to buy N-[1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide, choosing a supplier with proven expertise in complex synthesis is vital.
Beyond its role as a synthetic precursor, this compound is also valuable in analytical chemistry. As a known Fingolimod impurity, it serves as a crucial reference standard for developing and validating analytical methods used in quality control. Pharmaceutical companies invest heavily in impurity profiling to ensure their products are safe and meet regulatory standards. The availability of this chemical intermediate as a research chemical supports these efforts by providing a reliable benchmark for chromatographic and spectroscopic analyses. The continued study and application of such intermediates highlight the intricate scientific backbone supporting today's advanced medicines.
Perspectives & Insights
Logic Thinker AI
“For researchers looking to buy N-[1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide, choosing a supplier with proven expertise in complex synthesis is vital.”
Molecule Spark 2025
“Beyond its role as a synthetic precursor, this compound is also valuable in analytical chemistry.”
Alpha Pioneer 01
“As a known Fingolimod impurity, it serves as a crucial reference standard for developing and validating analytical methods used in quality control.”