In the realm of fine chemicals and pharmaceutical intermediates, a deep understanding of a compound's properties and applications is crucial for its effective utilization. (S)-N-Glycidylphthalimide, identified by CAS number 161596-47-0, is a prime example of such a compound, playing a pivotal role in various synthetic processes, most notably in the pharmaceutical industry.

Chemically, (S)-N-Glycidylphthalimide is characterized by its molecular formula C11H9NO3 and a molecular weight of 203.19 g/mol. It typically presents as a white crystalline powder, a form that is stable under recommended storage conditions, usually between 2-8°C under inert gas. Its solubility in common organic solvents like acetone and dichloromethane, coupled with its melting point around 102°C, makes it amenable to various reaction conditions. The presence of a chiral center, denoted by the 'S' configuration, is particularly significant for its use in stereoselective synthesis.

The primary application of (S)-N-Glycidylphthalimide lies in its function as a vital intermediate in the synthesis of blockbuster drugs. It is a critical precursor for the anticoagulant Rivaroxaban and the antibiotic Linezolid. The precise stereochemistry of the intermediate is instrumental in ensuring the correct three-dimensional structure of the final APIs, which directly impacts their therapeutic efficacy and safety profile. This makes the quality and enantiomeric purity of (S)-N-Glycidylphthalimide a non-negotiable factor for pharmaceutical manufacturers.

Beyond its pharmaceutical applications, the reactive epoxide group of (S)-N-Glycidylphthalimide allows it to be employed in other areas of chemical synthesis, such as the development of polymers, coatings, and specialty materials. Its ability to undergo ring-opening reactions and nucleophilic substitutions makes it a versatile building block for chemists exploring new molecular architectures.

For companies seeking to procure this essential intermediate, sourcing from reliable manufacturers is key. China has emerged as a significant hub for the production of high-quality pharmaceutical intermediates, including (S)-N-Glycidylphthalimide. Manufacturers in this region often boast advanced production facilities, adhere to strict quality control protocols, and offer competitive pricing. When purchasing, it is advisable to look for suppliers that can provide detailed specifications, certificates of analysis (COA), and safety data sheets (SDS), ensuring that the product meets the required purity and regulatory standards.

In conclusion, (S)-N-Glycidylphthalimide is a compound of immense importance in modern chemistry, particularly within the pharmaceutical sector. Its well-defined chemical properties and critical role in the synthesis of life-saving drugs underscore its value. By understanding its characteristics and sourcing it strategically from reputable suppliers, the industry can continue to drive innovation and deliver essential healthcare solutions.