NINGBO INNO PHARMCHEM CO.,LTD. is a leading provider of high-quality chemicals and reagents essential for various scientific disciplines, with a particular focus on the biotechnology and pharmaceutical sectors. Among our comprehensive offerings, protected amino acids play a critical role, especially in the intricate field of custom peptide manufacturing. One such vital compound is Z-Tyr(Bzl)-OH, which stands for N-alpha-Benzyloxycarbonyl-O-benzyl-L-tyrosine.

The synthesis of peptides, which are chains of amino acids, requires careful management of reactive functional groups on each amino acid. This is where protected amino acids come into play. Protecting groups temporarily block these reactive sites, preventing unwanted side reactions during the synthesis process and ensuring that the peptide chain grows in the desired sequence. Z-Tyr(Bzl)-OH is a prime example of such a protected amino acid, featuring a Benzyloxycarbonyl (Z or Cbz) group on the alpha-amino group and a Benzyl (Bzl) group on the phenolic hydroxyl group of the tyrosine side chain. These protecting groups are strategically chosen for their stability under certain reaction conditions and their selective removal at specific stages of the synthesis.

The primary application of Z-Tyr(Bzl)-OH lies in Solid Phase Peptide Synthesis (SPPS), a cornerstone technique in peptide manufacturing. In SPPS, the peptide is built sequentially on a solid support (resin). The Z-protected amino acid is coupled to the growing peptide chain, followed by the removal of the Z group to expose the alpha-amino group for the next amino acid addition. The benzyl ether protection on the tyrosine side chain is generally stable to the acidic conditions used to remove the Boc or Fmoc protecting groups from the alpha-amino terminus. It is typically cleaved off using stronger acidic conditions like hydrofluoric acid (HF) or trifluoromethanesulfonic acid (TFMSA) during the final cleavage of the peptide from the resin.

For companies engaged in custom peptide manufacturing, sourcing high-quality protected amino acids is paramount. The purity and consistency of these building blocks directly impact the yield and purity of the final peptide product. NINGBO INNO PHARMCHEM CO.,LTD. understands this critical requirement and ensures that our Z-Tyr(Bzl)-OH, with a guaranteed purity typically above 98% (HPLC), meets the stringent demands of peptide chemists. We also offer competitive pricing and flexible order quantities, making us a reliable partner for both research laboratories and larger production facilities.

Beyond custom peptide manufacturing, Z-Tyr(Bzl)-OH also finds utility as an intermediate in general organic synthesis and as a biochemical reagent. Its well-defined structure and reactive sites allow for further chemical modifications, contributing to the development of novel compounds and research tools. Our commitment to providing reliable peptide synthesis reagents and supporting advancements in chemical research is unwavering. By offering critical components like Z-Tyr(Bzl)-OH, NINGBO INNO PHARMCHEM CO.,LTD. empowers scientists and manufacturers to achieve groundbreaking results in their respective fields.