Sodium Starch Glycolate: A Key Ingredient for Effective Tablet Disintegration
In pharmaceutical science, the efficacy of a drug is intrinsically linked to its delivery system. For oral solid dosage forms like tablets, the speed and completeness of disintegration are critical factors influencing drug absorption and bioavailability. Sodium Starch Glycolate (SSG), chemically known as Sodium Carboxymethyl Starch (CAS No. 9063-38-1), is a highly valued excipient that excels in this regard. NINGBO INNO PHARMCHEM CO.,LTD. offers high-quality SSG, a testament to its importance in modern tablet formulation.
The primary attribute that makes SSG a preferred choice is its exceptional performance as a disintegrant. When incorporated into a tablet formulation, SSG rapidly swells upon contact with water. This swelling action generates internal pressure within the tablet, effectively breaking it apart into granules or primary particles. This process is fundamental to ensuring rapid drug release. As a sodium carboxymethyl starch tablet disintegrant, it guarantees that tablets break down efficiently in the stomach, allowing the active pharmaceutical ingredient (API) to dissolve and be absorbed into the bloodstream without delay. This makes it an ideal component for immediate-release formulations.
Moreover, SSG offers a significant advantage in terms of tablet quality. It contributes to improve tablet hardness disintegrant characteristics, meaning tablets formulated with SSG can be made harder and more resistant to chipping and breakage during handling and processing. This enhanced mechanical strength is crucial for the stability of the final product. The ability to improve hardness without hindering the disintegration process is a key benefit that sets SSG apart from some other disintegrants.
The applications of Sodium Starch Glycolate are not limited to tablets. It also serves as an effective suspension aid for liquid preparations. In suspensions, SSG helps to keep insoluble drug particles evenly dispersed, preventing them from settling at the bottom of the container. This ensures dose uniformity and patient compliance, especially in liquid formulations where consistent particle distribution is vital. The utility of sodium starch glycolate pharmaceutical excipient in both solid and liquid dosage forms highlights its versatility.
NINGBO INNO PHARMCHEM CO.,LTD. ensures that its Sodium Carboxymethyl Starch is a medicine grade starch ether, meaning it meets rigorous purity and quality standards set by regulatory bodies worldwide. This adherence to quality is paramount in the pharmaceutical industry, where the safety and efficacy of the final drug product are non-negotiable. Manufacturers can rely on our SSG as a dependable chemical reagent that consistently delivers superior performance. By choosing SSG from NINGBO INNO PHARMCHEM CO.,LTD., pharmaceutical companies can enhance the disintegration profiles of their tablets, improve overall product quality, and ensure the efficient delivery of active pharmaceutical ingredients, ultimately leading to better patient outcomes.
Perspectives & Insights
Nano Explorer 01
“It contributes to improve tablet hardness disintegrant characteristics, meaning tablets formulated with SSG can be made harder and more resistant to chipping and breakage during handling and processing.”
Data Catalyst One
“This enhanced mechanical strength is crucial for the stability of the final product.”
Chem Thinker Labs
“The ability to improve hardness without hindering the disintegration process is a key benefit that sets SSG apart from some other disintegrants.”