Sourcing 4-Formylphenylboronic Acid: Quality and Availability for Pharmaceutical Intermediates
For professionals in the pharmaceutical and fine chemical industries, securing a reliable supply of high-quality intermediates is fundamental to successful drug development and manufacturing. 4-Formylphenylboronic acid (CAS No: 87199-17-5) is one such crucial intermediate, essential for the synthesis of important medications. Understanding the specifications, applications, and sourcing strategies for this compound is vital for ensuring the integrity and efficiency of production pipelines.
The primary application driving the demand for 4-Formylphenylboronic acid is its function as a key intermediate in the synthesis of Atazanavir, an antiretroviral drug used to treat HIV infection, and Rucaparib, a treatment for certain cancers. The efficacy and availability of these life-saving drugs depend heavily on the consistent quality and timely delivery of their precursor materials. This places a significant emphasis on the purity and reliability of 4-Formylphenylboronic acid, typically specified with an assay of ≥98.0%.
When sourcing 4-Formylphenylboronic acid, it is imperative to partner with reputable suppliers who can guarantee product quality and consistency. Factors such as the physical appearance (white to light yellow crystal powder), precise CAS number, and molecular weight are critical identifiers of a reputable product. Furthermore, suppliers who provide comprehensive documentation, including certificates of analysis and safety data sheets, instill confidence in the material's suitability for pharmaceutical manufacturing.
The chemical industry recognizes the versatility of boronic acids, and 4-Formylphenylboronic acid, with its distinct aldehyde functional group, offers unique synthetic advantages. This versatility allows for its use in various organic synthesis pathways, beyond its primary pharmaceutical applications, making it a valuable compound for broader chemical research and development. Companies involved in custom synthesis or the production of specialized chemicals often list 4-Formylphenylboronic acid as a core offering.
Ensuring the availability of 4-Formylphenylboronic acid means supporting the continuous progress in medical treatments. For those tasked with procurement, a thorough understanding of the market dynamics, quality requirements, and the importance of this specific boronic acid intermediate is essential for making informed sourcing decisions. The reliable supply of 4-Formylphenylboronic acid directly contributes to making advanced therapies accessible to patients worldwide.
Perspectives & Insights
Core Pioneer 24
“Factors such as the physical appearance (white to light yellow crystal powder), precise CAS number, and molecular weight are critical identifiers of a reputable product.”
Silicon Explorer X
“Furthermore, suppliers who provide comprehensive documentation, including certificates of analysis and safety data sheets, instill confidence in the material's suitability for pharmaceutical manufacturing.”
Quantum Catalyst AI
“The chemical industry recognizes the versatility of boronic acids, and 4-Formylphenylboronic acid, with its distinct aldehyde functional group, offers unique synthetic advantages.”