For researchers and developers in the pharmaceutical industry, the reliable procurement of high-quality intermediates is a non-negotiable aspect of the drug development lifecycle. (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile (CAS 207557-35-5) is one such crucial compound, serving as a key building block, most notably for the synthesis of Vildagliptin, a widely prescribed medication for type 2 diabetes. Understanding how to source this specific chemical intermediate is vital for maintaining project timelines and ensuring the integrity of research and production.

The primary characteristic that researchers look for when sourcing (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile is its purity. Typically, specifications will indicate a purity level of ≥98.0% (HPLC), ensuring that the compound is free from significant impurities that could interfere with subsequent reactions or compromise the final product's quality. Beyond purity, other critical parameters include optical activity, which confirms the correct stereochemistry for pharmaceutical applications, and a well-defined appearance, often described as a white to off-white crystalline powder.

When considering where to buy (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, it is essential to engage with reputable manufacturers and suppliers who can provide comprehensive documentation. This includes Certificates of Analysis (CoA) detailing purity, spectroscopic data (like NMR), and safety data sheets (SDS). The CAS number, 207557-35-5, is a universal identifier that should be consistently used in all inquiries and orders to avoid confusion with similar compounds. NINGBO INNO PHARMCHEM CO.,LTD is committed to providing these essential documents and ensuring product traceability.

The global market for pharmaceutical intermediates is competitive, with numerous suppliers offering (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile. Researchers should evaluate suppliers based on their manufacturing capabilities, quality control systems, regulatory compliance (e.g., ISO certification), and customer service. Factors such as price, minimum order quantities, and lead times are also important considerations for bulk purchases. Exploring the chemical synthesis pathways and understanding the raw materials used can also provide insights into the reliability of the supply chain.

In summary, the successful procurement of (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile involves a meticulous approach to supplier selection and product verification. By prioritizing purity, reliable documentation, and a strong supplier relationship, researchers can ensure a consistent supply of this critical intermediate, thereby facilitating the efficient development and production of life-changing pharmaceuticals like Vildagliptin.