The Synthesis and Characterization of 4-Hydrazinobenzoic Acid Hydrochloride: A Deeper Look
Understanding the fundamental aspects of chemical compounds, including their synthesis and structural characteristics, is vital for their effective application. NINGBO INNO PHARMCHEM CO.,LTD. recognizes the importance of detailed knowledge regarding intermediates like 4-Hydrazinobenzoic Acid Hydrochloride. This article offers a closer look at its synthesis, crystallization, and the molecular interactions that define its behavior, providing valuable context for researchers and developers.
The synthesis of 4-Hydrazinobenzoic Acid Hydrochloride is a key process that dictates its purity and suitability for various applications, particularly as a pharmaceutical intermediate. The compound, with the chemical formula C7H9O2·Cl, has been successfully synthesized and characterized using advanced spectroscopic techniques such as FT-IR spectroscopy and X-ray diffraction. These methods allow scientists to confirm the compound's identity and purity, ensuring it meets the rigorous standards required for pharmaceutical and fine chemical applications.
The crystallographic analysis of 4-Hydrazinobenzoic Acid Hydrochloride reveals fascinating insights into its molecular architecture. It crystallizes as colorless needles within a triclinic system, space group Pˉ1. The specific cell parameters (a = 3.7176 Å, b = 5.9133 Å, c = 19.3631 Å, α = 87.841°, β = 88.924°, γ = 80.203°) and volume (V = 419.13 Å3) provide precise details about its solid-state structure. This level of detail is crucial for understanding its stability and reactivity in different environments, a key consideration for any chemical intermediate for drug development.
A significant aspect of its characterization involves the study of non-covalent interactions. The compound exhibits a complex three-dimensional framework formed by a combination of hydrogen bonds, including O-H⋯O, N-H⋯N, and N-H⋯Cl bonds. These interactions link the component ions, with each cation interacting with multiple anions. Calculations on Non-Covalent Interactions (NCI) further corroborate these findings, amplifying the crystallographic data concerning the interionic hydrogen bonds. This intricate network of interactions contributes to the compound's overall stability and physical properties, making it a reliable choice for organic synthesis.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing products that are not only effective but also well-understood. By offering detailed information on the synthesis and characterization of 4-Hydrazinobenzoic Acid Hydrochloride, we empower our clients to make informed decisions. Whether you are developing new pharmaceuticals or exploring novel chemical applications, understanding the fundamental properties of your intermediates, such as those involved in fine chemical manufacturing, is essential. We facilitate the purchase of 4-hydrazinobenzoic acid hydrochloride with confidence.
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“This intricate network of interactions contributes to the compound's overall stability and physical properties, making it a reliable choice for organic synthesis.”
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