At NINGBO INNO PHARMCHEM CO.,LTD., we understand that the quality of our chemical intermediates directly impacts the success of our clients' projects. This article provides a closer look at the synthesis of N-Acetyl-L-Valine (CAS: 96-81-1), a process that demands precision and adherence to established protocols. Understanding the synthesis is key to appreciating the value and reliability of this important compound.

The conventional synthesis of N-Acetyl-L-Valine begins with L-valine, a readily available amino acid, and acetic anhydride. The process typically involves dissolving L-valine in water and then gradually adding a sodium hydroxide solution to maintain the appropriate pH. The mixture is cooled to low temperatures, usually between 0-5°C, before acetic anhydride is added dropwise. This controlled addition, often repeated multiple times, is crucial for managing the exothermic reaction and ensuring efficient acetylation of the amino group.

Following the acetylation step, the reaction mixture is acidified, typically with hydrochloric acid, to precipitate the N-Acetyl-L-Valine. The resulting slurry is then allowed to crystallize, often overnight, to maximize product recovery. The solid product is subsequently collected by filtration, washed to remove residual impurities, and dried. The overall yield is typically high, reflecting the efficiency of this well-established method. The ability to buy N-Acetyl-L-Valine that has undergone such controlled synthesis ensures consistent quality.

For chemical professionals, the ability to purchase N-Acetyl-L-Valine from a trusted supplier like NINGBO INNO PHARMCHEM CO.,LTD. simplifies their workflow. It eliminates the need for in-house synthesis, saving time and resources, and guarantees access to a high-purity product. The price of N-Acetyl-L-Valine is a consideration, but the benefits of sourcing from a specialized manufacturer are substantial.

In conclusion, the synthesis of N-Acetyl-L-Valine is a robust chemical process that yields a vital intermediate. Its applications as a ligand in organic synthesis and as a pharmaceutical intermediate highlight its importance. We are committed to providing chemical professionals with access to high-quality N-Acetyl-L-Valine, facilitating advancements in their respective fields.