In the realm of chemical synthesis, certain molecules serve as foundational building blocks that enable the creation of more complex and valuable compounds. Among these essential components is [(2S)-1-ethylpyrrolidin-2-yl]methanamine, identified by its CAS number 22795-99-9. This chiral amine, with its distinct molecular structure and properties, plays a significant role in various chemical applications, most notably in the pharmaceutical sector.

The chemical profile of [(2S)-1-ethylpyrrolidin-2-yl]methanamine is characterized by its molecular formula C7H16N2 and a molecular weight of 128.22. As a clear, colorless to faintly yellow liquid, it possesses specific physical attributes such as a boiling point of 50-52 °C (lit.) and a refractive index of n20/D 1.4670 (lit.). Crucially, its chiral nature is demonstrated by its optical activity, with specific rotation values often cited around -107º (c=1, methanol). This defined stereochemistry is what makes it highly valuable in enantioselective synthesis.

The primary application driving the demand for [(2S)-1-ethylpyrrolidin-2-yl]methanamine is its function as a key pharmaceutical intermediate. It is an indispensable precursor in the synthesis of Levonsulpiride, a medication used for treating gastrointestinal and psychiatric conditions. The requirement for a specific enantiomer in pharmaceutical synthesis underscores the importance of sourcing this intermediate with guaranteed stereochemical integrity. Beyond pharmaceuticals, its amine functionality and cyclic structure make it a versatile reagent in general organic synthesis, facilitating the development of novel compounds and materials.

For research and manufacturing purposes, reliable access to this chemical building block is essential. Companies involved in drug development or chemical research often seek to buy (2S)-1-ethylpyrrolidin-2-yl]methanamine from reputable suppliers. Manufacturers based in China, such as NINGBO INNO PHARMCHEM CO., LTD., are key players in this market, providing high-quality intermediates. When procuring this compound, focusing on suppliers that offer consistent quality, detailed analytical data, and competitive pricing ensures a smooth and effective integration into synthesis processes. Understanding the properties and applications of such chiral building blocks is fundamental to driving innovation in chemistry and medicine.