NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing detailed insights into the chemical compounds that drive innovation in various industries, particularly pharmaceuticals. Today, we focus on 2-(4-fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene, a compound identified by its CAS number 898566-17-1, and its essential role as a pharmaceutical intermediate.

The chemical structure of this molecule is key to its utility. It features a thiophene ring, a five-membered heterocyclic aromatic ring containing sulfur. Attached to this core are a 4-fluorophenyl group and a substituted benzyl group, specifically a 2-methylphenyl group bearing an iodine atom at the 5-position. This complex arrangement, encapsulated in the molecular formula C18H14FIS and a molecular weight of approximately 408.27 g/mol, provides the specific reactivity and structural features required for its downstream applications.

Understanding the iodo-methylphenyl thiophene chemical properties is crucial for chemists working with this compound. It is typically supplied as a white powder with a high purity, often exceeding 99%. Physical properties such as density (around 1.533 g/cm³) and boiling point (approximately 450.2 °C at 760 mmHg) provide further insights into its behavior under various conditions. These detailed specifications are vital for ensuring successful synthesis and handling in laboratory and industrial settings.

As a critical building block for SGLT inhibitors, its application in the synthesis of Canagliflozin is well-documented. The precise arrangement of its functional groups allows for efficient coupling and modification reactions necessary to build the final drug molecule. The demand for such complex organic synthesis building blocks reflects the ongoing advancements in medicinal chemistry and drug development.

For researchers and procurement specialists, accessing accurate information about compounds like 2-(4-fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene is fundamental. NINGBO INNO PHARMCHEM CO.,LTD. aims to be a comprehensive resource, offering insights into the chemical identity, applications, and sourcing of these vital materials. The consistent availability and high quality of such intermediates are indispensable for the progress of pharmaceutical research and manufacturing.