Methyl 4-ethynylbenzoate, bearing the CAS number 3034-86-4, is a fascinating molecule for chemists, prized for its dual functionality and utility in organic synthesis. This white powder, with a molecular formula of C10H8O2 and a molecular weight of 160.17 g/mol, presents a unique combination of an ethynyl group and a methyl ester attached to a benzene ring. Its boiling point is reported around 239.4°C, and it typically melts between 92-94°C, although some sources cite a broader range for its appearance as a powder to crystal. Sparingly soluble in water, it finds its primary applications as a crucial methyl 4-ethynylbenzoate pharmaceutical intermediate and a versatile organic chemistry building block.

The synthesis of Methyl 4-ethynylbenzoate often involves transformations of related benzoic acid derivatives or propiolic acid esters. Common synthetic routes might include Sonogashira coupling reactions where a terminal alkyne is coupled with an aryl halide, or esterification reactions of 4-ethynylbenzoic acid. Understanding these pathways is essential for those looking to buy Methyl 4-ethynylbenzoate or to synthesize it in-house. The efficiency and yield of these synthesis methods directly impact the cost and availability of high purity methyl 4-ethynylbenzoate, making it a key consideration for bulk purchasers.

The chemical properties of Methyl 4-ethynylbenzoate make it a subject of interest for numerous research applications. As an organic chemistry building block, its ethynyl group is highly reactive, participating readily in cycloadditions, metal-catalyzed cross-couplings, and other addition reactions. The ester group can also be readily modified, allowing for further diversification of molecular structures. This versatility is why CAS 3034-86-4 chemical synthesis is a popular area of study and application in various chemical industries.

The continuous exploration of new synthetic pathways and applications for Methyl 4-ethynylbenzoate by NINGBO INNO PHARMCHEM CO.,LTD. underscores its importance in driving innovation within the chemical sector. Researchers and manufacturers alike benefit from the availability of such fundamental, yet powerful, chemical intermediates.