At NINGBO INNO PHARMCHEM CO.,LTD., we specialize in providing detailed chemical profiles of essential compounds. 2-(Bromomethyl)benzonitrile (CAS 22115-41-9) is a fine chemical intermediate with a well-defined chemical personality, crucial for its diverse applications in organic synthesis and pharmaceutical manufacturing. Its structure, properties, and reactivity are key to its value in the chemical industry.

The molecular formula C8H6BrN reveals a benzonitrile core substituted with a bromomethyl group at the ortho position. This structure gives rise to its characteristic properties: typically appearing as a white to light yellow crystal powder. The compound has a molecular weight of approximately 196.05 g/mol. Key physical properties, such as a melting point of around 70-74 °C and a boiling point of 111 °C at 1.5 mmHg, provide essential data for handling and processing. The 2-(bromomethyl)benzonitrile synthesis methods are designed to achieve high purity, often exceeding 98%, ensuring its suitability for demanding applications.

The primary application of 2-(Bromomethyl)benzonitrile lies in its role as an intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Its utility in the production of Alogliptin, an oral antidiabetic agent, highlights its importance in the pharmaceutical sector. The precise control over reaction conditions during its use is vital for successful alogliptin intermediate production. Beyond pharmaceuticals, this versatile organic intermediate finds use in various other fine chemical manufacturing processes, where its reactive bromomethyl group can be readily substituted or modified.

When considering the purchase of 2-(bromomethyl)benzonitrile, understanding these detailed chemical and physical properties is essential for ensuring its effective use in your specific applications. From its appearance as a crystalline powder to its reactivity in complex organic reactions, each characteristic contributes to its significant role in modern chemistry.