Understanding the detailed chemical profile of an intermediate is crucial for its effective utilization in pharmaceutical synthesis. 5-(4-Bromophenyl)-4,6-pyrimidinediol, identified by CAS number 706811-25-8, is a compound that possesses a unique set of physical and chemical properties making it highly valuable in the pharmaceutical industry. NINGBO INNO PHARMCHEM CO.,LTD. is a key supplier of this compound, ensuring its availability for critical manufacturing processes.

Physically, 5-(4-Bromophenyl)-4,6-pyrimidinediol is typically presented as a white powder. This physical state is convenient for handling and processing in laboratory and industrial settings. Its molecular formula, C10H7BrN2O2, and a molecular weight of 267.079, provide the fundamental chemical identity. The reported density of 1.7±0.1 g/cm³ and a high boiling point of 429.6±45.0 °C at 760 mmHg, along with a flash point of 213.6±28.7 °C, indicate its stability under typical processing conditions. These properties are essential considerations for organic synthesis and process scale-up.

The primary application for this intermediate, as highlighted by NINGBO INNO PHARMCHEM CO.,LTD.'s offerings, is its role in the synthesis of Macitentan. Macitentan is a vital medication used to treat pulmonary arterial hypertension, and the consistent supply of high-purity intermediates like 5-(4-Bromophenyl)-4,6-pyrimidinediol is critical for its production. The demand for this Macitentan intermediate is driven by the therapeutic importance of the final drug product.

Beyond its role in Macitentan synthesis, the inherent chemical structure of 5-(4-Bromophenyl)-4,6-pyrimidinediol makes it an attractive building block for broader drug discovery initiatives. Researchers in medicinal chemistry can utilize this compound to explore new synthetic pathways and develop novel chemical entities with a wide range of potential therapeutic applications. The availability of such versatile pharmaceutical intermediates is a cornerstone of innovation in the life sciences.

NINGBO INNO PHARMCHEM CO.,LTD. focuses on ensuring that the chemical intermediate supplied meets rigorous purity standards, often stated as ≥98.0%. This level of purity is crucial to prevent unwanted side reactions and to guarantee the efficacy and safety of the resulting Active Pharmaceutical Ingredients (APIs). For those seeking to purchase 5-(4-bromophenyl)-4,6-pyrimidinediol, partnering with a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures that these quality benchmarks are consistently met.

In summary, the detailed chemical and physical properties of 5-(4-Bromophenyl)-4,6-pyrimidinediol underscore its importance as a versatile and indispensable intermediate in the pharmaceutical industry. NINGBO INNO PHARMCHEM CO.,LTD. remains committed to facilitating advancements in pharmaceutical manufacturing by providing this critical compound with unwavering quality and reliability.